Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL439393 | 0.86 | RXFP1 (0.74) | RXFP1TDP1FGFR1FGFR4L3MBTL1 | |
| SCHEMBL8604610 | 0.86 | RXFP1 (0.56) | RXFP1TDP1FGFR1FGFR4L3MBTL1 | |
| SCHEMBL13802232 | 0.85 | RXFP1 (0.59) | RXFP1TDP1FGFR1FGFR4MEN1 | |
| SCHEMBL11430538 | 0.84 | RXFP1 (0.57) | RXFP1TDP1FGFR1FGFR4L3MBTL1 | |
| SCHEMBL6415721 | 0.84 | RXFP1 (0.57) | RXFP1TDP1FGFR1FGFR4L3MBTL1 | |
| SCHEMBL8866580 | 0.82 | RXFP1 (0.56) | RXFP1TDP1FGFR1FGFR4L3MBTL1 | |
| SCHEMBL9067803 | 0.82 | RXFP1 (0.56) | RXFP1TDP1L3MBTL1POLBMEN1 | |
| SCHEMBL29990643 | 0.81 | PRSS1 (0.47) | RXFP1MEN1KMT2AHDAC1HDAC6 | |
| SCHEMBL4351620 | 0.81 | TDP1 (0.49) | RXFP1TDP1FGFR1FGFR4L3MBTL1 | |
| SCHEMBL11436457 | 0.81 | RXFP1 (0.54) | RXFP1TDP1FGFR1FGFR4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105566371-A | Silicone (meth)acrylamide monomer, polymer, ophthalmic lens, and contact lens | JOHNSON & JOHNSON VISION CARE | 2016-05-11 | — | — | CN | disclosed |
| CN-103025745-B | Silicone (meth) acrylamide monomers, polymers, ophthalmic lenses, and contact lenses | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2016-01-20 | — | — | CN | disclosed |
| EP-2547688-B1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | JOHNSON & JOHNSON VISION CARE (US) | 2014-12-17 | — | — | EP | disclosed |
| US-8623934-B2 | Silicone (meth)acrylamide monomer, polymer, ophthalmic lens, and contact lens | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2014-01-07 | — | — | US | disclosed |
| US-8541483-B2 | Silicone (meth)acrylamide monomer, polymer, ophthalmic lens, and contact lens | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-09-24 | — | — | US | disclosed |
| US-20130197176-A1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-08-01 | — | — | US | disclosed |
| US-20130178594-A1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-07-11 | — | — | US | disclosed |
| US-8415405-B2 | Silicone (meth)acrylamide monomer, polymer, ophthalmic lens, and contact lens | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2013-04-09 | — | — | US | disclosed |
| CN-103025745-A | Silicone (meth) acrylamide monomers, polymers, ophthalmic lenses, and contact lenses | JOHNSON & JOHNSON VISION CARE | 2013-04-03 | — | — | CN | disclosed |
| EP-2547688-A1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | Johnson & Johnson Vision Care, Inc. (US) | 2013-01-23 | — | — | EP | disclosed |
| US-20110237766-A1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | JOHNSON & JOHNSON VISION CARE, INC. | 2011-09-29 | — | — | US | disclosed |
| WO-2011116206-A1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2011-09-22 | — | — | WO | disclosed |
| US-20080177002-A1 | Thermoplastic Resin Composition, Optical Film, And Process For Producing Film | JSR CORPORATION (JP) | 2008-07-24 | — | — | US | disclosed |
| US-20080038669-A1 | NON-TRULY-SPHERICAL HIGH-MOLECULAR FINE PARTICLES, PROCESS FOR PRODUCING THE SAME, INKJET INK COMPOSITION CONTAINING FINE PARTICLES, LITHOGRAPHIC PRINTING PLATE USING THE SAME, PROCESS FOR PRODUCING PRINTING PLATE, AND ELECTROPHORETIC PARTICLES-CONTAINING COMPOSITION CONTAINING FINE PARTICLES | FUJIFILM CORPORATION (JP) | 2008-02-14 | — | — | US | disclosed |
| CN-101098931-A | Thermoplastic resin composition, optical film, and process for producing film | JSR CORP (JP) | 2008-01-02 | — | — | CN | disclosed |
| EP-1837374-A1 | THERMOPLASTIC RESIN COMPOSITION, OPTICAL FILM, AND PROCESS FOR PRODUCING FILM | JSR Corporation (JP) | 2007-09-26 | — | — | EP | disclosed |
| EP-0911153-B1 | Image forming method | KONISHIROKU PHOTO IND (JP) | 2003-12-10 | — | — | EP | disclosed |
| US-6174646-B1 | IMAGEWISE HEATING OR EXPOSING IMAGE FORMING MATERIAL TO LASER WHEREIN IMAGE FORMING MATERIAL COMPRISES SUPPORT HAVING RADIATION SENSITIVE LAYER CONTAINING DYE, AN ACID GENERATING COMPOUND CAPABLE OF GENERATING ACID ON IRRADIATION | KONICA CORPORATION (JP) | 2001-01-16 | — | — | US | disclosed |
| EP-0911153-A1 | Image forming method | KONICA CORPORATION (JP) | 1999-04-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130197176-A1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | CRYAA, MGMT, UACA | RXFP1 3827/4885TDP1 3811/4885FGFR1 4257/4885 |
| US-20110237766-A1 | SILICONE (METH)ACRYLAMIDE MONOMER, POLYMER, OPHTHALMIC LENS, AND CONTACT LENS | CRYAA, MGMT, UACA | RXFP1 3827/4885TDP1 3811/4885FGFR1 4257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.