Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24523908 | 0.93 | METAP2 (0.43) | METAP2PTGDR2CYP19A1CYP1A2MEN1 | |
| SCHEMBL24523751 | 0.91 | METAP2 (0.39) | METAP2PTGDR2CYP19A1CYP1A2MEN1 | |
| SCHEMBL24523753 | 0.90 | METAP2 (0.41) | METAP2PTGDR2CYP19A1CYP1A2MEN1 | |
| SCHEMBL24523739 | 0.86 | METAP2 (0.37) | METAP2PTGDR2CYP19A1CYP1A2MEN1 | |
| SCHEMBL24524246 | 0.81 | ALDH1A1 (0.35) | METAP2PTGDR2CYP19A1CYP1A2MEN1 | |
| SCHEMBL24524243 | 0.81 | PRKDC (0.33) | CYP1A2ALDH1A1CYP2C19TP53SLC22A12 | |
| SCHEMBL24524240 | 0.77 | BRD1 (0.37) | ALDH1A1MAPK1LMNAMAPTTDP1 | |
| SCHEMBL24523765 | 0.75 | PTGDR2 (0.40) | METAP2PTGDR2CYP19A1MEN1KMT2A | |
| SCHEMBL24523768 | 0.74 | MAOA (0.38) | CYP19A1CYP1A2ALDH1A1CYP2C19KDM4E | |
| SCHEMBL24524241 | 0.74 | BRD1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129116-A1 | INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |