Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.45 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | LYN | P07948 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | FER | P16591 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24523791 | 0.92 | ABCG2 (0.44) | ABCG2CLK4ABCB1LMNAKDM4E | |
| SCHEMBL24523719 | 0.85 | MEN1 (0.39) | MEN1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL24523786 | 0.84 | ABCG2 (0.40) | ABCG2CLK4ABCB1LMNAMEN1 | |
| SCHEMBL24523724 | 0.84 | GABRA1 (0.39) | CSNK1A1CSNK1DCSNK1G2ALDH1A3MYC | |
| SCHEMBL24523804 | 0.84 | GABRA1 (0.39) | CSNK1A1CSNK1DCSNK1G2ALDH1A3MYC | |
| SCHEMBL24523722 | 0.84 | MEN1 (0.38) | MEN1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL16939597 | 0.83 | ABCG2 (0.39) | ABCG2ABCB1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL24523765 | 0.81 | PTGDR2 (0.40) | MEN1KMT2AGABRA1GABRG2GABRB3 | |
| SCHEMBL24198267 | 0.81 | CYP1A2 (0.42) | ABCG2CLK4ABCB1LMNAKDM4E | |
| SCHEMBL24523831 | 0.80 | ENPP3 (0.37) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129116-A1 | INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |