Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24523748 | 0.97 | MAOA (0.39) | MAOAMAOBCYP19A1KDM4EALDH1A1 | |
| SCHEMBL24523768 | 0.93 | MAOA (0.38) | MAOAMAOBCYP19A1KDM4EALDH1A1 | |
| SCHEMBL24523757 | 0.93 | MAOA (0.38) | MAOAMAOBCYP19A1KDM4EALDH1A1 | |
| SCHEMBL24524238 | 0.92 | MAOA (0.37) | MAOAMAOBCYP19A1KDM4EALDH1A1 | |
| SCHEMBL24523761 | 0.86 | SLC22A12 (0.37) | MAOAMAOBCYP19A1KDM4EALDH1A1 | |
| SCHEMBL24523756 | 0.85 | PIM1 (0.40) | — | |
| SCHEMBL24523763 | 0.82 | MCL1 (0.43) | — | |
| SCHEMBL24523772 | 0.81 | CA1 (0.36) | MAOAMAOBKDM4EALDH1A1HPGD | |
| SCHEMBL24524245 | 0.81 | TRPA1 (0.34) | MAOAIMPDH2 | |
| SCHEMBL24524244 | 0.79 | MAP4K1 (0.37) | ALDH1A1IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129116-A1 | INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |