SCHEMBL24524232

SCHEMBL24524232

Clc1c(I)cnc2c1C1c3ccccc3C2c2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
GAA P10253 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24528269 0.81 MEN1 (0.35) MEN1GAAKMT2A
SCHEMBL26218564 0.71 MEN1 (0.39) MEN1GAAKMT2A
SCHEMBL24524224 0.66
SCHEMBL24524160 0.63 MAOA (0.34) MEN1GAAKMT2A
SCHEMBL24528476 0.63 ACHE (0.35)
SCHEMBL13453232 0.62 MEN1 (0.46) MEN1GAAKMT2A
SCHEMBL16723344 0.62 MEN1 (0.46) MEN1GAAKMT2A
SCHEMBL24524210 0.62
SCHEMBL20061792 0.61 KMT2A (0.39) MEN1GAAKMT2A
SCHEMBL601463 0.61 MAOA (0.50) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023161168-A1 AROMATIC HETREOCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-08-31 WO disclosed
WO-2023161167-A1 NITROGENOUS HETEROCYCLES FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-08-31 WO disclosed
WO-2022129113-A1 NITROGENOUS HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-06-23 WO disclosed
WO-2022129114-A1 NITROGENOUS COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-06-23 WO disclosed
WO-2022129116-A1 INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS MERCK PATENT GMBH (DE) 2022-06-23 WO disclosed