Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24524187 | 0.85 | MAOA (0.36) | NPSR1KDM4EALDH1A1GAA | |
| SCHEMBL24524551 | 0.84 | CLK1 (0.35) | ARIMPDH2POLBSMN1; SMN2NPSR1 | |
| SCHEMBL24524270 | 0.81 | CLK1 (0.35) | ARIMPDH2POLBSMN1; SMN2NPSR1 | |
| SCHEMBL24524305 | 0.79 | HTR1A (0.33) | AR | |
| SCHEMBL24524283 | 0.79 | — | — | |
| SCHEMBL24524552 | 0.79 | KDM4E (0.34) | KDM4EALDH1A1CASP1 | |
| SCHEMBL24523770 | 0.76 | IMPDH2 (0.38) | IMPDH2SMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL24523731 | 0.75 | IMPDH2 (0.33) | IMPDH2SMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL24524506 | 0.74 | — | — | |
| SCHEMBL24524315 | 0.74 | AR (0.31) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129116-A1 | INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |