Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29759272 | 1.00 | HTR2A (0.36) | HTR2AHTR2CPOLBCYP11B1CYP11B2 | |
| SCHEMBL24526702 | 0.90 | HTR2A (0.38) | HTR2AHTR2CPOLBCYP11B1CYP11B2 | |
| SCHEMBL29759212 | 0.89 | HCAR1 (0.38) | HTR2AHTR2CKDM5AKDM5BOPRL1 | |
| SCHEMBL24526557 | 0.89 | HCAR1 (0.38) | HTR2AHTR2CKDM5AKDM5BOPRL1 | |
| SCHEMBL6164489 | 0.82 | DGAT2 (0.45) | CA12CA1CA2CA9GRM5 | |
| SCHEMBL24527049 | 0.81 | HTR2A (0.43) | HTR2AHTR2CPOLBCYP11B1CYP11B2 | |
| SCHEMBL24526583 | 0.81 | GRIN3B (0.36) | — | |
| SCHEMBL24526826 | 0.77 | KDM4E (0.38) | POLBCYP11B1CYP11B2CA12CA1 | |
| SCHEMBL24526566 | 0.76 | ADCY10 (0.39) | POLBCYP11B1CYP11B2CA12CA1 | |
| SCHEMBL29759314 | 0.76 | ADCY10 (0.39) | POLBCYP11B1CYP11B2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129047-A2 | NOVEL MODULATORS OF THE NMDA RECEPTOR | H. LUNDBECK A/S (DK) | 2022-06-23 | — | — | WO | disclosed |