SCHEMBL2452850

SCHEMBL2452850

O=C1C=CC=c2cc3c(cc21)=Cc1ccccc1C3=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
LMNA P02545 1/20 0.41
BCHE P06276 1/20 0.41
POLB P06746 1/20 0.41
PTPRC P08575 1/20 0.41
MAPT P10636 1/20 0.41
THRB P10828 1/20 0.41
PKM P14618 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
PTPN1 P18031 1/20 0.41
ACHE P22303 1/20 0.41
CES1 P23141 1/20 0.41
RECQL P46063 1/20 0.41
HSD17B10 Q99714 1/20 0.41
PTPN22 Q9Y2R2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL440760 0.90 CDC25B (0.38) IDO1MEN1KMT2AKDM4EALDH1A1
SCHEMBL26205058 0.84 NQO1 (0.31)
SCHEMBL3444764 0.83 MEN1 (0.48) IDO1MEN1KMT2AKDM4EALDH1A1
SCHEMBL126239 0.75 CDC25B (0.33) IDO1CDC25BMAOAMAOBAKT1
SCHEMBL5207877 0.75 CDC25B (0.36) IDO1MEN1KMT2AKDM4EALDH1A1
SCHEMBL8936319 0.75 GPR84 (0.33) CES1
SCHEMBL11039168 0.71
SCHEMBL11039148 0.71
SCHEMBL4076256 0.71 IDO1 (0.35) IDO1MEN1KMT2AKDM4EALDH1A1
SCHEMBL29534849 0.70 PTPRC (0.46) IDO1MEN1KMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230213863-A1 COMPOUND, RESIST UNDERLAYER FILM COMPOSITION INCLUDING SAME, AND RESIST UNDERLAYER FILM DONGJIN SEMICHEM CO., LTD. (KR) 2023-07-06 US disclosed
US-20230213863-A1 COMPOUND, RESIST UNDERLAYER FILM COMPOSITION INCLUDING SAME, AND RESIST UNDERLAYER FILM DONGJIN SEMICHEM CO., LTD. (KR) 2023-07-06 US disclosed
US-8895725-B2 Use of 9, 10-anthraquinone compounds SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) 2014-11-25 US disclosed
US-20110224414-A1 USE OF 9, 10-ANTHRAQUINONE COMPOUNDS SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY (CN) 2011-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224414-A1 USE OF 9, 10-ANTHRAQUINONE COMPOUNDS HCCS, CYC1, C1S IDO1 1885/4885MEN1 4181/4885KMT2A 3695/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.