Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24528670 | 0.99 | RAD52 (0.35) | RAD52MAPK1ALDH1A1POLBUSP2 | |
| SCHEMBL24528631 | 0.97 | RAD52 (0.36) | RAD52MAPK1ALDH1A1POLBUSP2 | |
| SCHEMBL24528607 | 0.83 | TLR9 (0.36) | MAPK1ALDH1A1POLBTLR9MAPT | |
| SCHEMBL24528713 | 0.78 | PDE4B (0.41) | MAPK1ALDH1A1POLBUSP2LMNA | |
| SCHEMBL24528695 | 0.73 | KDM4E (0.34) | RAD52MAPK1ALDH1A1POLBLMNA | |
| SCHEMBL24528655 | 0.72 | KDM4E (0.34) | RAD52MAPK1ALDH1A1POLBLMNA | |
| SCHEMBL24528677 | 0.72 | KDM4E (0.34) | RAD52MAPK1ALDH1A1POLBLMNA | |
| SCHEMBL24528599 | 0.72 | KDM4E (0.33) | RAD52MAPK1ALDH1A1POLBLMNA | |
| SCHEMBL24528639 | 0.71 | ATM (0.37) | ALDH1A1LMNATLR9KDM4E | |
| SCHEMBL29680708 | 0.70 | GSK3B (0.41) | MAPK1ALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129376-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE|TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2022-06-23 | — | — | WO | disclosed |