Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.59 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3307690 | 1.00 | ADRB1 (0.67) | ADRB1KCNH2PRMT6ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL1803475 | 0.98 | ADRB1 (0.65) | ADRB1KCNH2PRMT6ALDH1A1MAPT | |
| SCHEMBL12991 | 0.98 | ADRB1 (0.69) | ADRB1KCNH2PRMT6ALDH1A1MAPT | |
| SCHEMBL8264176 | 0.94 | ADRB1 (0.69) | ADRB1KCNH2PRMT6ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL27827352 | 0.92 | ADRB1 (0.67) | ADRB1KCNH2PRMT6ALDH1A1MAPT | |
| SCHEMBL10373770 | 0.89 | ADRB1 (0.74) | ADRB1KCNH2ALDH1A1MAPTRAB9A | |
| SCHEMBL11103700 | 0.89 | ADRB1 (0.74) | ADRB1KCNH2ALDH1A1MAPTRAB9A | |
| SCHEMBL22944451 | 0.86 | ADRB1 (0.51) | ADRB1KCNH2PRMT6ALDH1A1MAPT | |
| Nitrogen SCHEMBL11690640 | 0.86 | ADRB1 (0.56) | ADRB1KCNH2PRMT6ALDH1A1MAPT | |
| SCHEMBL22685038 | 0.84 | ALDH1A1 (0.59) | ADRB1PRMT6ALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791137-B1 | PYRAZOLOPYRIDINE DERIVATIVES, PREPARATION PROCESS THEREFOR AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2019-01-23 | — | — | EP | disclosed |
| US-9486422-B2 | Small molecule inhibitors of Mcl-1 and the uses of thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-11-08 | — | — | US | disclosed |
| WO-2015179559-A2 | PYRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | ABIDE THERAPEUTICS, INC. (US) | 2015-11-26 | — | — | WO | disclosed |