Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MLLT3 | P42568 | 1/20 | 0.46 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29723791 | 1.00 | HPGDS (0.48) | HPGDSL3MBTL1MLLT3MLLT1EPHX2 | |
| SCHEMBL23015033 | 0.84 | L3MBTL1 (0.61) | L3MBTL1EPHX2SMN1; SMN2CYP3A4NR1H4 | |
| SCHEMBL22893169 | 0.83 | HPGDS (0.46) | HPGDSL3MBTL1MLLT1EPHX2NR1H4 | |
| SCHEMBL29723785 | 0.77 | KMT2A (0.53) | SMN1; SMN2CYP1A2CHRM4HDAC6 | |
| SCHEMBL24529732 | 0.77 | KMT2A (0.53) | SMN1; SMN2CYP1A2CHRM4HDAC6 | |
| SCHEMBL29723794 | 0.77 | HPGD (0.46) | HPGDSL3MBTL1EPHX2SMN1; SMN2NR1H4 | |
| SCHEMBL24529730 | 0.77 | HPGD (0.46) | HPGDSL3MBTL1EPHX2SMN1; SMN2NR1H4 | |
| SCHEMBL21490291 | 0.75 | EPHX2 (0.64) | EPHX2SMN1; SMN2CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL12103897 | 0.74 | KMT2A (0.56) | EPHX2SMN1; SMN2NR1H4HDAC1HDAC3 | |
| SCHEMBL16496066 | 0.74 | HPGDS (0.71) | HPGDSL3MBTL1SMN1; SMN2HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240034722-A1 | PRETARGETING IMAGING AGENTS | ELI LILLY AND COMPANY | 2024-02-01 | — | — | US | disclosed |
| EP-4262885-A1 | PRETARGETING IMAGING AGENTS | Eli Lilly and Company (US) | 2023-10-25 | — | — | EP | disclosed |
| CN-116783177-A | Pretargeting imaging agent | 伊莱利利公司 | 2023-09-19 | — | — | CN | disclosed |
| WO-2022132924-A1 | PRETARGETING IMAGING AGENTS | ELI LILLY AND COMPANY (US) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022132924-A1 | PRETARGETING IMAGING AGENTS | ELI LILLY AND COMPANY (US) | 2022-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240034722-A1 | PRETARGETING IMAGING AGENTS | CD47, NECTIN4, LGALS3BP | HPGDS 1475/4885L3MBTL1 2463/4885MLLT3 3298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.