Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24529801 | 0.83 | HPGDS (0.48) | HPGDSL3MBTL1EPHX2NR1H4XDH | |
| SCHEMBL29723791 | 0.83 | HPGDS (0.48) | HPGDSL3MBTL1EPHX2NR1H4XDH | |
| SCHEMBL16110424 | 0.81 | L3MBTL1 (0.66) | HPGDSL3MBTL1EPHX2MAPK1HDAC2 | |
| SCHEMBL25678192 | 0.78 | CA2 (0.53) | HPGDSL3MBTL1EPHX2NR1H4 | |
| SCHEMBL16109524 | 0.78 | EPHX2 (0.56) | L3MBTL1EPHX2HDAC1ROCK2ROCK1 | |
| SCHEMBL23015033 | 0.77 | L3MBTL1 (0.61) | L3MBTL1EPHX2NR1H4HDAC1MAPK1 | |
| SCHEMBL217496 | 0.73 | NNMT (0.49) | L3MBTL1HDAC1HDAC6 | |
| SCHEMBL25511293 | 0.72 | KMT2A (0.41) | EPHX2NR1H4XDHHDAC1HDAC6 | |
| SCHEMBL12103897 | 0.72 | KMT2A (0.56) | EPHX2NR1H4HDAC1HDAC3HDAC4 | |
| SCHEMBL12388325 | 0.72 | HCAR3 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210008229-A1 | TARGETED PHOTOACOUSTIC AGENTS AND USES THEREOF | MCMASTER UNIVERSITY (CA) | 2021-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210008229-A1 | TARGETED PHOTOACOUSTIC AGENTS AND USES THEREOF | PPOX, PAM, MB | HPGDS 571/4885L3MBTL1 3041/4885EPHX2 545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.