Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 9/20 | 0.55 |
| ▸ | TRPA1 | O75762 | 7/20 | 0.50 |
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL480562 | 0.91 | TRPA1 (0.59) | ABL1TRPA1TRPV4MAPTKMT2A | |
| SCHEMBL480598 | 0.88 | TRPA1 (0.61) | ABL1TRPA1TRPV4KMT2AMEN1 | |
| SCHEMBL2455704 | 0.86 | ABL1 (0.72) | ABL1TRPA1MAPTKMT2AMEN1 | |
| SCHEMBL480671 | 0.85 | TRPA1 (0.58) | ABL1TRPA1TRPV4KMT2AMEN1 | |
| SCHEMBL2449783 | 0.84 | TRPA1 (0.60) | ABL1TRPA1TRPV4KMT2AMEN1 | |
| SCHEMBL4418963 | 0.81 | GSTO1 (0.66) | TRPA1TRPV4MAPTKMT2A | |
| SCHEMBL15417595 | 0.81 | ABL1 (0.56) | ABL1TRPA1MAPTKMT2AMEN1 | |
| SCHEMBL13570250 | 0.80 | TRPA1 (0.46) | ABL1TRPA1TRPV4KMT2AMEN1 | |
| SCHEMBL4417203 | 0.80 | TRPA1 (0.61) | ABL1TRPA1TRPV4MAPTKMT2A | |
| SCHEMBL4411028 | 0.80 | TRPA1 (0.60) | TRPA1TRPV4MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011114184-A1 | AMIDES OF HETEROCYCLIC COMPOUNDS AS TRPA1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2011-09-22 | — | — | WO | disclosed |