Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 3/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13687283 | 1.00 | SMPD1 (0.44) | SMPD1TSHRLMNADNM1ADH1B | |
| SCHEMBL13687268 | 1.00 | SMPD1 (0.44) | SMPD1TSHRLMNADNM1ADH1B | |
| SCHEMBL755748 | 1.00 | SMPD1 (0.44) | SMPD1TSHRLMNADNM1ADH1B | |
| SCHEMBL2130926 | 1.00 | SMPD1 (0.44) | SMPD1TSHRLMNADNM1ADH1B | |
| SCHEMBL36477 | 0.98 | SMPD1 (0.41) | SMPD1TSHRLMNADNM1ADH1B | |
| SCHEMBL13686628 | 0.91 | TSHR (0.40) | SMPD1TSHRDNM1 | |
| Cyclohexane SCHEMBL6913818 | 0.90 | SMPD1 (0.42) | SMPD1TSHRLMNAFDPSGPR84 | |
| SCHEMBL6762424 | 0.85 | OPRM1 (0.37) | SMPD1TSHRLMNAOPRM1 | |
| SCHEMBL11697875 | 0.83 | TSHR (0.38) | SMPD1TSHRLMNADNM1ADH1B | |
| SCHEMBL20599262 | 0.83 | TSHR (0.38) | SMPD1TSHRLMNADNM1ADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2132248-B1 | ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN | SIKA TECHNOLOGY AG (CH) | 2016-07-13 | — | — | EP | disclosed |
| CN-101687775-B | Aldimines and compositions comprising aldamine | SIKA TECHNOLOGY AG | 2015-05-06 | — | — | CN | disclosed |
| US-8519038-B2 | Aldimines and compositions comprising aldimine | SIKA TECHNOLOGY AG (CH) | 2013-08-27 | — | — | US | disclosed |
| US-20120220736-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2012-08-30 | — | — | US | disclosed |
| US-8252859-B2 | Aldimines and compositions comprising aldimine | SIKA TECHNOLOGY AG (CH) | 2012-08-28 | — | — | US | disclosed |
| EP-1934172-B1 | COMPOUNDS CONTAINING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2011-09-28 | — | — | EP | disclosed |
| US-20100101455-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2010-04-29 | — | — | US | disclosed |
| EP-2178828-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDAMINE | Sika Technology AG (CH) | 2010-04-28 | — | — | EP | disclosed |
| CN-101687775-A | Aldimines and compositions comprising aldamine | SIKA TECHNOLOGY AG | 2010-03-31 | — | — | CN | disclosed |
| EP-2132248-A1 | ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN | Sika Technology AG (CH) | 2009-12-16 | — | — | EP | disclosed |
| WO-2008116928-A1 | ALDIMINES WITH REACTIVE GROUPS COMPRISING ACTIVE HYDROGEN | SIKA TECHNOLOGY AG (CH) | 2008-10-02 | — | — | WO | disclosed |
| EP-1975190-A1 | Aldimines with reactive groups containing active hydrogen | Sika Technology AG (CH) | 2008-10-01 | — | — | EP | disclosed |
| EP-1934169-A1 | ALDIMINES COMPRISING REACTIVE GROUPS CONTAINING ACTIVE HYDROGEN, AND USE THEREOF | Sika Technology AG (CH) | 2008-06-25 | — | — | EP | disclosed |
| EP-1934172-A1 | COMPOUNDS CONTAINING ALDIMINE | Sika Technology AG (CH) | 2008-06-25 | — | — | EP | disclosed |
| EP-1775284-A1 | Compounds comprising aldimine groups | Sika Technology AG (CH) | 2007-04-18 | — | — | EP | disclosed |
| EP-1772447-A1 | Aldimines with reactive groups comprising active hydrogen, and their use | Sika Technology AG (CH) | 2007-04-11 | — | — | EP | disclosed |
| WO-2007036572-A1 | COMPOUNDS CONTAINING ALDIMINE | SIKA TECHNOLOGY AG (CH) | 2007-04-05 | — | — | WO | disclosed |
| WO-2007036571-A1 | ALDIMINES COMPRISING REACTIVE GROUPS CONTAINING ACTIVE HYDROGEN, AND USE THEREOF | SIKA TECHNOLOGY AG (CH) | 2007-04-05 | — | — | WO | disclosed |
| US-5049631-A | Heat resistant | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-09-17 | — | — | US | disclosed |
| US-4299941-A | MODIFIED WITH POLYBASIC ACID POLYALLYL ESTER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120220736-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | ALDOA, ALDH7A1, ALDH3A1 | SMPD1 4677/4885TSHR 4835/4885LMNA 674/4885 |
| US-20100101455-A1 | ALDIMINES AND COMPOSITIONS COMPRISING ALDIMINE | ALDH7A1, ILK, ALDH3A1 | SMPD1 4570/4885TSHR 4884/4885LMNA 404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.