Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 15/20 | 0.83 |
| ▸ | FGFR1 | P11362 | 11/20 | 0.83 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.83 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.83 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.83 |
| ▸ | PDGFRB | P09619 | 11/20 | 0.82 |
| ▸ | PDGFRA | P16234 | 11/20 | 0.82 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.82 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.82 |
| ▸ | ABL1 | P00519 | 9/20 | 0.72 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.72 |
| ▸ | EGFR | P00533 | 5/20 | 0.72 |
| ▸ | WEE1 | P30291 | 2/20 | 0.71 |
| ▸ | KIT | P10721 | 4/20 | 0.70 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.68 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.68 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.68 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.68 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.68 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3458816 | 0.90 | SRC (1.00) | SRCFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL29508114 | 0.90 | SRC (1.00) | SRCFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL2251720 | 0.89 | FGFR1 (0.66) | SRCFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL5764062 | 0.85 | FGFR1 (1.00) | SRCFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL2252253 | 0.84 | FGFR1 (0.61) | SRCFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL20563464 | 0.84 | RIPK2 (0.66) | SRCFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL5762046 | 0.84 | SRC (1.00) | SRCFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL1249524 | 0.84 | FGFR1 (1.00) | SRCFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL2247993 | 0.83 | FGFR1 (0.59) | SRCFGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL1334768 | 0.83 | SRC (1.00) | SRCFGFR1FGFR2FGFR4FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220194937-A1 | PROTEIN KINASE INHIBITORS AND USES THEREOF FOR THE TREATMENT OF DISEASES AND CONDITIONS | UNIVERSITY OF HOUSTON SYSTEM | 2022-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220194937-A1 | PROTEIN KINASE INHIBITORS AND USES THEREOF FOR THE TREATMENT OF DISEASES AND CONDITIONS | RIPK2, RIPK1, RIPK4 | SRC 1967/4885FGFR1 424/4885FGFR2 456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.