Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350498 | 0.83 | DNMT1 (0.39) | DHFRDNMT1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL351208 | 0.80 | DHFR (0.32) | DHFRDNMT1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL24535284 | 0.76 | — | — | |
| SCHEMBL24535388 | 0.72 | — | — | |
| SCHEMBL24535273 | 0.72 | OPRM1 (0.30) | — | |
| SCHEMBL24535298 | 0.68 | SLC6A4 (0.31) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL24535288 | 0.67 | SCN1A (0.33) | SMN1; SMN2ALDH1A1KMT2AHPGD | |
| SCHEMBL30122801 | 0.67 | DNMT1 (0.47) | DHFRDNMT1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL366604 | 0.67 | KDM4E (0.40) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL27263879 | 0.66 | ALDH1A1 (0.53) | DHFRDNMT1SMN1; SMN2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022132048-A1 | PHOSPHORUS COMPOUNDS AND METHODS THEREOF | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2022-06-23 | — | — | WO | disclosed |