Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 17/20 | 0.65 |
| ▸ | ABL1 | P00519 | 17/20 | 0.65 |
| ▸ | SRC | P12931 | 17/20 | 0.65 |
| ▸ | PIK3CD | O00329 | 16/20 | 0.65 |
| ▸ | PIK3CA | P42336 | 16/20 | 0.65 |
| ▸ | PIK3CB | P42338 | 16/20 | 0.65 |
| ▸ | PIK3CG | P48736 | 16/20 | 0.65 |
| ▸ | HCK | P08631 | 16/20 | 0.65 |
| ▸ | EGFR | P00533 | 15/20 | 0.65 |
| ▸ | KDR | P35968 | 15/20 | 0.65 |
| ▸ | EPHB4 | P54760 | 15/20 | 0.65 |
| ▸ | PRKDC | P78527 | 15/20 | 0.65 |
| ▸ | PI4KB | Q9UBF8 | 12/20 | 0.65 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.58 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.58 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.58 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.58 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.58 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.57 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19294557 | 0.89 | MTOR (0.71) | MTORABL1SRCPIK3CDPIK3CA | |
| SCHEMBL19299699 | 0.81 | PIK3CD (0.62) | MTORABL1SRCPIK3CDPIK3CA | |
| SCHEMBL15497301 | 0.76 | MTOR (0.79) | MTORABL1SRCPIK3CDPIK3CA | |
| SCHEMBL15497291 | 0.76 | MTOR (0.79) | MTORABL1SRCPIK3CDPIK3CA | |
| SCHEMBL7895680 | 0.76 | MTOR (0.79) | MTORABL1SRCPIK3CDPIK3CA | |
| SCHEMBL30353302 | 0.75 | MTOR (0.54) | MTORABL1SRCPIK3CDPIK3CA | |
| SCHEMBL16117324 | 0.75 | BMPR1B (0.80) | MTORABL1SRCPIK3CDPIK3CA | |
| SCHEMBL20112902 | 0.75 | MTOR (0.74) | MTORABL1SRCPIK3CDPIK3CA | |
| SCHEMBL30405300 | 0.74 | PIK3CD (0.56) | MTORABL1SRCPIK3CDPIK3CA | |
| Sapanisertib SCHEMBL7902875 | 0.73 | MTOR (1.00) | MTORABL1SRCPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220193242-A1 | IMMUNOPHILIN-DEPENDENT INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220193242-A1 | IMMUNOPHILIN-DEPENDENT INHIBITORS AND USES THEREOF | CD74, CD2BP2, SERPINB1 | MTOR 4486/4885ABL1 2123/4885SRC 1950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.