Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21424031 | 0.76 | PANK3 (0.46) | PANK3RAB9AALDH1A1DEGS1MEN1 | |
| SCHEMBL24535611 | 0.74 | PANK3 (0.37) | PANK3RAB9APOLBALDH1A1MEN1 | |
| SCHEMBL26501697 | 0.73 | RORC (0.41) | PANK3RAB9APOLBALDH1A1DEGS1 | |
| SCHEMBL21424096 | 0.68 | PANK3 (0.48) | PANK3ALDH1A1DEGS1KMT2AMAPT | |
| SCHEMBL21424019 | 0.67 | PANK3 (0.57) | PANK3DEGS1TSHRCNR2KCNH2 | |
| SCHEMBL2688260 | 0.66 | DEGS1 (0.46) | RAB9AALDH1A1DEGS1MLYCDMEN1 | |
| SCHEMBL24536033 | 0.65 | PANK3 (0.33) | PANK3RAB9AMEN1KMT2A | |
| SCHEMBL11161614 | 0.64 | TP53 (0.58) | RAB9AALDH1A1MEN1KMT2ARORC | |
| SCHEMBL31717602 | 0.63 | PANK3 (1.00) | PANK3 | |
| SCHEMBL19748700 | 0.63 | PANK3 (1.00) | PANK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133034-A1 | METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) | 2022-06-23 | — | — | WO | disclosed |