Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 6/20 | 0.33 |
| ▸ | USP5 | P45974 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24536032 | 0.80 | MEN1 (0.53) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL21424098 | 0.71 | PANK3 (0.37) | PANK3MEN1KMT2A | |
| SCHEMBL24536034 | 0.68 | PANK3 (0.34) | PANK3 | |
| SCHEMBL30942641 | 0.67 | TKT (0.33) | HSD11B1 | |
| SCHEMBL26501786 | 0.66 | RAB9A (0.36) | USP5GSK3BNPC1RAB9A | |
| SCHEMBL21424018 | 0.66 | PANK3 (0.41) | PANK3KMT2A | |
| SCHEMBL24535612 | 0.65 | PANK3 (0.46) | PANK3MEN1KMT2ARAB9A | |
| SCHEMBL11436465 | 0.64 | ALDH1A1 (0.50) | USP5MEN1KMT2AGSK3BNPC1 | |
| SCHEMBL16832891 | 0.63 | EGLN2 (0.33) | — | |
| SCHEMBL21424037 | 0.63 | PANK3 (0.41) | PANK3MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133034-A1 | METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) | 2022-06-23 | — | — | WO | disclosed |