Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PANK3 | Q9H999 | 5/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.30 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24536020 | 0.82 | PANK3 (0.35) | PANK3HDAC1HDAC6 | |
| SCHEMBL21423857 | 0.75 | PANK3 (0.36) | PANK3UCHL1 | |
| SCHEMBL12101028 | 0.72 | PLA2G4A (0.47) | TRPA1PLA2G4AUCHL1 | |
| SCHEMBL26501801 | 0.71 | POLB (0.33) | TRPA1 | |
| SCHEMBL24535611 | 0.70 | PANK3 (0.37) | PANK3HDAC1HDAC6 | |
| SCHEMBL21424026 | 0.68 | PANK3 (0.36) | PANK3UCHL1 | |
| SCHEMBL24536032 | 0.68 | MEN1 (0.53) | HDAC1 | |
| SCHEMBL24536033 | 0.68 | PANK3 (0.33) | PANK3 | |
| SCHEMBL21424027 | 0.66 | CYP1A2 (0.42) | PANK3 | |
| SCHEMBL27588098 | 0.65 | CYP1A2 (0.39) | TRPA1UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133034-A1 | METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) | 2022-06-23 | — | — | WO | disclosed |