Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24536033 | 0.80 | PANK3 (0.33) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7079689 | 0.72 | RAB9A (0.66) | MEN1KMT2AALDH1A1RECQLLMNA | |
| SCHEMBL21424097 | 0.71 | MAPT (0.48) | MEN1KMT2AALDH1A1RECQLLMNA | |
| SCHEMBL10070187 | 0.71 | NR1H4 (0.59) | MEN1KMT2AALDH1A1RECQLLMNA | |
| SCHEMBL22241270 | 0.68 | ALDH1A1 (0.81) | MEN1KMT2AALDH1A1RECQLLMNA | |
| SCHEMBL393300 | 0.68 | RAB9A (0.56) | MEN1KMT2AALDH1A1RECQLLMNA | |
| SCHEMBL24536034 | 0.68 | PANK3 (0.34) | HDAC1 | |
| SCHEMBL11353543 | 0.67 | HSD17B3 (0.62) | MEN1KMT2AALDH1A1RECQLLMNA | |
| SCHEMBL10070209 | 0.67 | RAB9A (0.64) | MEN1KMT2AALDH1A1RECQLLMNA | |
| SCHEMBL10070185 | 0.67 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1RECQLLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133034-A1 | METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR | ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) | 2022-06-23 | — | — | WO | disclosed |