SCHEMBL245370

SCHEMBL245370

O=Cc1ccc(OCC(F)(F)F)cc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.48
KDM4E B2RXH2 5/20 0.48
SMN1; SMN2 Q16637 4/20 0.47
LMNA P02545 2/20 0.47
MAPT P10636 2/20 0.47
HPGD P15428 1/20 0.47
CYP2A6 P11509 1/20 0.47
RAB9A P51151 2/20 0.44
NPC1 O15118 1/20 0.44
DRD1 P21728 1/20 0.43
ALDH1A3 P47895 1/20 0.42
KMT2A Q03164 2/20 0.42
MEN1 O00255 1/20 0.41
STS P08842 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
POLB P06746 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3032947 0.85 ALDH1A1 (0.45) ALDH1A1KDM4ESMN1; SMN2LMNAMAPT
SCHEMBL8546197 0.85 ALDH1A1 (0.45) ALDH1A1KDM4ESMN1; SMN2LMNAMAPT
SCHEMBL21510512 0.84 KMT2A (0.48) ALDH1A1KDM4ESMN1; SMN2LMNAMAPT
SCHEMBL28516376 0.83 ALDH1A1 (0.50) ALDH1A1KDM4ESMN1; SMN2LMNAMAPT
SCHEMBL498377 0.82 ALDH1A1 (0.56) ALDH1A1KDM4ESMN1; SMN2LMNAMAPT
SCHEMBL3045965 0.82 ALDH1A1 (0.42) ALDH1A1KDM4ESMN1; SMN2LMNAMAPT
SCHEMBL3036856 0.82 SMN1; SMN2 (0.47) ALDH1A1KDM4ESMN1; SMN2LMNAMAPT
SCHEMBL1982503 0.81 ALDH1A1 (0.53) ALDH1A1KDM4ESMN1; SMN2LMNAMAPT
SCHEMBL2998505 0.80 CHRNB2 (0.46) ALDH1A1KDM4ESMN1; SMN2LMNAMAPT
SCHEMBL5357292 0.80 ALDH1A1 (0.52) ALDH1A1KDM4ESMN1; SMN2LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2721020-B1 METALLOENZYME INHIBITOR COMPOUNDS VIAMET PHARMACEUTICALS NC INC (US) 2019-01-23 EP claimed
CN-103842355-A Metalloenzyme inhibitor compounds VIAMET PHARMACEUTICALS INC 2014-06-04 CN claimed
CN-103764646-A Metalloenzyme inhibitor compounds VIAMET PHARMACEUTICALS INC 2014-04-30 CN claimed
JP-2204471-A None JP disclosed
US-20260083864-A1 CONTRAST AGENTS FOR USE IN DIAGNOSTIC COMPUTED TOMOGRAPHY IMAGING BAYER AG (DE) 2026-03-26 US disclosed
EP-4611747-A1 IMIDAZOLE COMPOUNDS AND THEIR USE AS SODIUM CHANNEL INHIBITORS Genep Inc. (US) 2025-09-10 EP disclosed
EP-4583926-A1 CONTRAST AGENTS FOR USE IN DIAGNOSTIC COMPUTED TOMOGRAPHY IMAGING Bayer Aktiengesellschaft (DE) 2025-07-16 EP disclosed
EP-4308551-B1 NEW CONTRAST AGENT FOR USE IN MAGNETIC RESONANCE IMAGING BAYER AG (DE) 2025-04-09 EP disclosed
EP-3733186-B1 NOVEL DIHYDROQUINAZOLINONE COMPOUND OR PHARMACOLOGICALLY ACCEPTABLE SALT, AND CELL GROWTH INHIBITOR JAPANESE FOUND FOR CANCER RES (JP) 2024-12-04 EP disclosed
WO-2024097171-A1 IMIDAZOLE COMPOUNDS AND THEIR USE AS SODIUM CHANNEL INHIBITORS GENEP INC. (US) 2024-05-10 WO disclosed
WO-2024052550-A1 CONTRAST AGENTS FOR USE IN DIAGNOSTIC COMPUTED TOMOGRAPHY IMAGING BAYER AKTIENGESELLSCHAFT (DE) 2024-03-14 WO disclosed
EP-1880720-A1 SUBSTITUTED ACRYLAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME Daiichi Sankyo Company, Limited (JP) 2008-01-23 EP disclosed
WO-2005042521-A2 PIPERIDINYL-AND PIPERAZINYL-SULFONYLMETHYL HYDROXAMIC ACIDS AND THEIR USE AS PROTEASE INHIBITORS PHARMACIA CORPORATION (US) 2005-05-12 WO disclosed
EP-0387315-B1 FLUORINATED ALKOXYL COMPOUNDS MERCK PATENT GMBH (DE) 1993-12-08 EP disclosed
JP-H02204471-A PRODUCTION OF ARYLMETHYL (TRIFLUOROETHOXYPHENYL)KETONE RHONE POULENC CHIM 1990-08-14 JP disclosed
US-4925863-A 1,3-DI(1,2,4-TRIAZOL-1-YL)-2-PROPANOL DERIVATIVES SUBSTITUTED WITH A STYRYL GROUP IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-05-15 US disclosed
US-4888340-A Insecticides pyrazolines, compositions and use SCHERING AKTIENGESELLSCHAFT (DE) 1989-12-19 US disclosed
US-4754067-A REACTING A SYMETRICAL DIAMINOGUANIDINE WITH HYDROXYLAMINE HYDROCHLORIDE AMERICAN CYANAMID COMPANY (US) 1988-06-28 US disclosed
US-4649148-A Insecticidal uses of diaminoguanidine hydrazone compounds AMERICAN CYANAMID COMPANY (US) 1987-03-10 US disclosed
US-4575560-A ANTIFEEDING AGENTS AMERICAN CYANAMID COMPANY (US) 1986-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083864-A1 CONTRAST AGENTS FOR USE IN DIAGNOSTIC COMPUTED TOMOGRAPHY IMAGING CA13, CCR1, GALC ALDH1A1 1811/4885KDM4E 4512/4885SMN1; SMN2 2305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.