Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 4/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 3/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 3/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16363611 | 0.92 | EPHX1 (0.54) | EPHX1GAASMN1; SMN2RAB9ABRD4 | |
| SCHEMBL24539765 | 0.90 | EPHX1 (0.54) | EPHX1GAASMN1; SMN2RAB9ATPSAB1 | |
| SCHEMBL8243750 | 0.81 | GAA (0.63) | EPHX1GAABCHE | |
| SCHEMBL22134987 | 0.80 | EPHX1 (0.44) | EPHX1GAASMN1; SMN2RAB9A | |
| SCHEMBL21786685 | 0.79 | EPHX1 (0.46) | EPHX1GAASMN1; SMN2RAB9ANR1H4 | |
| SCHEMBL22134964 | 0.78 | EPHX1 (0.66) | EPHX1GAABCHE | |
| SCHEMBL10879403 | 0.78 | EPHX1 (0.65) | EPHX1GAATPSAB1TPSD1TPSG1 | |
| SCHEMBL20928290 | 0.78 | EPHX1 (0.65) | EPHX1GAABCHEMEN1KMT2A | |
| SCHEMBL22136179 | 0.77 | EPHX1 (0.69) | EPHX1GAABCHE | |
| SCHEMBL16374741 | 0.77 | EPHX1 (0.64) | EPHX1GAABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240238430-A1 | ANTI-CEA IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2024-07-18 | — | — | US | disclosed |
| US-20240238430-A1 | ANTI-CEA IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2024-07-18 | — | — | US | disclosed |
| US-20220195066-A1 | ANTI-CEA IMMUNOCONJUGATES, AND USES THEREOF | BOLT BIOTHERAPEUTICS, INC. (US) | 2022-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240238430-A1 | ANTI-CEA IMMUNOCONJUGATES, AND USES THEREOF | CA14, CA12, CA13 | EPHX1 689/4885GAA 253/4885SMN1; SMN2 4719/4885 |
| US-20220195066-A1 | ANTI-CEA IMMUNOCONJUGATES, AND USES THEREOF | EPHX2, FAAH2, CYP8B1 | EPHX1 5/4885GAA 1173/4885SMN1; SMN2 4786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.