Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | F13A1 | P00488 | 1/20 | 0.45 |
| ▸ | ESRRG | P62508 | 6/20 | 0.41 |
| ▸ | ESRRB | O95718 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24540726 | 1.00 | KDM4E (0.45) | KDM4EF13A1ESRRGESRRBNPC1 | |
| SCHEMBL29112286 | 1.00 | KDM4E (0.45) | KDM4EF13A1ESRRGESRRBNPC1 | |
| SCHEMBL29112444 | 0.93 | ESRRG (0.43) | KDM4EF13A1ESRRGESRRBNPC1 | |
| SCHEMBL29112441 | 0.93 | ESRRG (0.43) | KDM4EF13A1ESRRGESRRBNPC1 | |
| SCHEMBL24540664 | 0.93 | ESRRG (0.43) | KDM4EF13A1ESRRGESRRBNPC1 | |
| SCHEMBL24540469 | 0.91 | MEN1 (0.39) | KDM4EGAACYP2C19MEN1KMT2A | |
| SCHEMBL24540251 | 0.91 | GAA (0.44) | NPC1GAAMAPTCYP2C19RAB9A | |
| SCHEMBL24540521 | 0.91 | ALDH1A1 (0.46) | NPC1GAARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL29112469 | 0.91 | GAA (0.44) | NPC1GAAMAPTCYP2C19RAB9A | |
| SCHEMBL29112470 | 0.91 | GAA (0.44) | NPC1GAAMAPTCYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829532-A | Substituted cyclohexane carboxamides, their preparation and their therapeutic use | 赛诺菲 | 2023-09-29 | — | — | CN | disclosed |