Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24540521 | 1.00 | ALDH1A1 (0.46) | ALDH1A1HPGDTSHRPOLBGAA | |
| SCHEMBL29112470 | 0.91 | GAA (0.44) | ALDH1A1TSHRGAAKMT2AMEN1 | |
| SCHEMBL29112499 | 0.91 | MEN1 (0.39) | ALDH1A1HPGDTSHRPOLBGAA | |
| SCHEMBL29112469 | 0.91 | GAA (0.44) | ALDH1A1TSHRGAAKMT2AMEN1 | |
| SCHEMBL24540726 | 0.91 | KDM4E (0.45) | GAAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL29112500 | 0.91 | MEN1 (0.39) | ALDH1A1HPGDTSHRPOLBGAA | |
| SCHEMBL24540251 | 0.91 | GAA (0.44) | ALDH1A1TSHRGAAKMT2AMEN1 | |
| SCHEMBL24540469 | 0.91 | MEN1 (0.39) | ALDH1A1HPGDTSHRPOLBGAA | |
| SCHEMBL29112288 | 0.91 | KDM4E (0.45) | GAAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL29112286 | 0.91 | KDM4E (0.45) | GAAKMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116829532-A | Substituted cyclohexane carboxamides, their preparation and their therapeutic use | 赛诺菲 | 2023-09-29 | — | — | CN | disclosed |