Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24540459 | 0.85 | TRPM8 (0.49) | TRPM8TRPV1EPHX1P2RX4 | |
| SCHEMBL891394 | 0.82 | TRPM8 (0.50) | TRPM8TRPV1EPHX1P2RX4 | |
| SCHEMBL24540511 | 0.82 | TRPM8 (0.50) | TRPM8TRPV1EPHX1P2RX4 | |
| SCHEMBL2628610 | 0.82 | TRPM8 (0.50) | TRPM8TRPV1EPHX1P2RX4 | |
| SCHEMBL19058455 | 0.82 | TRPM8 (0.50) | TRPM8TRPV1EPHX1P2RX4 | |
| SCHEMBL2159887 | 0.82 | NPC1 (0.53) | TRPM8TRPV1EPHX1 | |
| SCHEMBL2160133 | 0.82 | TRPM8 (0.53) | TRPM8TRPV1EPHX1P2RX4 | |
| SCHEMBL12805446 | 0.81 | TRPM8 (0.58) | TRPM8TRPV1EPHX1 | |
| SCHEMBL10073499 | 0.81 | TRPM8 (0.58) | TRPM8TRPV1EPHX1 | |
| SCHEMBL15857921 | 0.81 | TRPM8 (0.58) | TRPM8TRPV1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133027-A1 | SUBSTITUTED CYCLOHEXANECARBOXAMIDES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2022-06-23 | — | — | WO | disclosed |