Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24540260 | 0.85 | TRPM8 (0.53) | TRPM8TRPV1EPHX1P2RX4 | |
| SCHEMBL12805446 | 0.81 | TRPM8 (0.58) | TRPM8TRPV1EPHX1 | |
| SCHEMBL10073499 | 0.81 | TRPM8 (0.58) | TRPM8TRPV1EPHX1 | |
| SCHEMBL15857921 | 0.81 | TRPM8 (0.58) | TRPM8TRPV1EPHX1 | |
| SCHEMBL1603431 | 0.78 | TRPM8 (0.55) | TRPM8TRPV1EPHX1ALDH1A1 | |
| SCHEMBL24540799 | 0.78 | TRPM8 (0.55) | TRPM8TRPV1EPHX1ALDH1A1 | |
| SCHEMBL15054395 | 0.78 | TRPM8 (0.55) | TRPM8TRPV1EPHX1ALDH1A1 | |
| SCHEMBL12805171 | 0.78 | TRPM8 (0.58) | TRPM8TRPV1EPHX1P2RX4ALDH1A1 | |
| SCHEMBL11419516 | 0.78 | TRPM8 (0.58) | TRPM8TRPV1EPHX1P2RX4ALDH1A1 | |
| SCHEMBL14580775 | 0.77 | TRPM8 (0.68) | TRPM8EPHX1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133027-A1 | SUBSTITUTED CYCLOHEXANECARBOXAMIDES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2022-06-23 | — | — | WO | disclosed |