Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29730163 | 1.00 | DPP8 (0.35) | DPP8DPP9MIFRAB9ANPC1 | |
| SCHEMBL29730116 | 0.88 | DPP8 (0.34) | DPP8DPP9MIFRAB9ANPC1 | |
| SCHEMBL29730079 | 0.83 | DPP8 (0.35) | DPP8DPP9IDO1NR1H4CYP17A1 | |
| SCHEMBL29730095 | 0.81 | MAPKAPK2 (0.36) | DPP8DPP9RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24543134 | 0.81 | MAPKAPK2 (0.36) | DPP8DPP9RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL29730100 | 0.81 | RET (0.35) | DPP8DPP9RAB9ANPC1IDO1 | |
| SCHEMBL31736645 | 0.81 | MIF (0.38) | DPP8DPP9MIFRAB9ANPC1 | |
| SCHEMBL29730109 | 0.81 | MAPK1 (0.43) | DPP8DPP9RAB9ANPC1KDM4E | |
| SCHEMBL27202134 | 0.81 | MAPK1 (0.43) | DPP8DPP9RAB9ANPC1KDM4E | |
| SCHEMBL27202128 | 0.81 | KDM4E (0.33) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129933-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | Pandeia Therapeutics Limited (GB) | 2022-06-23 | — | — | WO | disclosed |