SCHEMBL31736645

SCHEMBL31736645

CC(C)(C)OC(=O)NC12CC(c3ccc(C=O)cc3)(C1)C2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MIF P14174 1/20 0.38
▸ RAB9A P51151 4/20 0.37
▸ NPC1 O15118 3/20 0.37
▸ RECQL P46063 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ MAPT P10636 2/20 0.36
▸ KDM4E B2RXH2 3/20 0.36
▸ ALDH1A1 P00352 2/20 0.36
▸ DPP8 Q6V1X1 3/20 0.36
▸ DPP9 Q86TI2 3/20 0.36
▸ DRD2 P14416 3/20 0.33
▸ HPGD P15428 2/20 0.33
▸ MAPK10 P53779 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ RORC P51449 1/20 0.32
▸ NFKB1 P19838 1/20 0.32
▸ NFKB2 Q00653 1/20 0.32
▸ RELA Q04206 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29525089 0.83 DRD2 (0.47) MAPTALDH1A1DPP8DPP9DRD2
SCHEMBL21238259 0.83 DPP8 (0.43) RAB9ANPC1DPP8DPP9MAPK10
SCHEMBL28392276 0.82 LMNA (0.43) SMN1; SMN2MAPTALDH1A1DPP8DPP9
SCHEMBL24622249 0.82 EPHX2 (0.38) MIFRAB9ANPC1RECQLSMN1; SMN2
SCHEMBL26388824 0.82 MIF (0.36) MIFRAB9ANPC1RECQLSMN1; SMN2
SCHEMBL29730163 0.81 DPP8 (0.35) MIFRAB9ANPC1RECQLSMN1; SMN2
SCHEMBL24543133 0.81 DPP8 (0.35) MIFRAB9ANPC1RECQLSMN1; SMN2
SCHEMBL29525490 0.81 RORC (0.41) MAPTDPP8DPP9RORC
SCHEMBL31737017 0.81 DPP8 (0.38) ALDH1A1DPP8DPP9DRD2HPGD
SCHEMBL31736668 0.81 CA1 (0.39) SMN1; SMN2MAPTALDH1A1DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245178-A1 PAK4, CSTF2, OR CSTF2T PROTEIN DEGRADERS, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS INNOVO THERAPEUTICS, INC. (US) 2025-11-27 — — WO disclosed
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