Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27207275 | 0.85 | POLB (0.33) | KDM4EALDH1A1 | |
| SCHEMBL27202108 | 0.85 | POLB (0.33) | KDM4EALDH1A1 | |
| SCHEMBL24543133 | 0.81 | DPP8 (0.35) | KDM4E | |
| SCHEMBL29730163 | 0.81 | DPP8 (0.35) | KDM4E | |
| SCHEMBL27202166 | 0.80 | GABRP (0.33) | KDM4E | |
| SCHEMBL27202119 | 0.77 | SMN1; SMN2 (0.42) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL27202115 | 0.76 | ALDH1A1 (0.34) | ALDH1A1L3MBTL1 | |
| SCHEMBL23933107 | 0.71 | ALDH1A1 (0.37) | KDM4EALDH1A1 | |
| SCHEMBL29730116 | 0.69 | DPP8 (0.34) | KDM4E | |
| SCHEMBL2911125 | 0.68 | RAB9A (0.46) | KDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132450-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | ACADIA PHARMACEUTICALS INC. | 2024-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132450-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | GPR88, GPR65, GPR68 | KDM4E 4242/4885ALDH1A1 2127/4885L3MBTL1 3949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.