SCHEMBL2454344

SCHEMBL2454344

CON=C(C(=O)O)c1nsc(N)n1

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2454341 1.00 LMNA (0.38) LMNAGAAMAPT
SCHEMBL8574244 1.00 LMNA (0.38) LMNAGAAMAPT
Hydrochloric Acid SCHEMBL8478125 0.98 LMNA (0.37) LMNAGAAMAPT
SCHEMBL8569731 0.89 LMNA (0.31) LMNAGAAMAPT
SCHEMBL9815219 0.89 LMNA (0.31) LMNAGAAMAPT
SCHEMBL10333301 0.86
SCHEMBL9199085 0.86
SCHEMBL3710407 0.86 LMNA (0.32) LMNAGAAMAPT
SCHEMBL2456035 0.86 LMNA (0.32) LMNAGAAMAPT
SCHEMBL3710405 0.86 LMNA (0.32) LMNAGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112295741-B Test method for recovering and concentrating sulfide ore 江西浒坑钨业有限公司 2022-11-11 CN claimed
CN-112295741-A Test method for recovering and concentrating sulfide ore 江西浒坑钨业有限公司 2021-02-02 CN claimed
CN-111606869-A Protection method for carboxyl of ceftobiprole active thioester intermediate 山西千岫制药有限公司 2020-09-01 CN claimed
CN-103570749-A Cefozopran preparation technology ANHUI YOUCARE KAIYUE PHARMACEUTICAL CO LTD 2014-02-12 CN claimed
WO-2010089729-A1 PROCESSES FOR THE PREPARATION OF CEFOZOPRAN, ITS SALTS AND POLYMORPHIC FORMS THEREOF RANBAXY LABORATORIES LIMITED (IN) 2010-08-12 WO claimed
US-4585872-A CEPHALOSPORIN ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1986-04-29 US claimed
CN-112295741-B Test method for recovering and concentrating sulfide ore 江西浒坑钨业有限公司 2022-11-11 CN disclosed
US-11267826-B2 Penicillin-binding protein inhibitors VenatoRx Pharmaceuticals, Inc. (US) 2022-03-08 US disclosed
US-11028103-B2 Derivatized 3-styryl-cephalosporins GLADIUS PHARMACEUTICALS CORPORATION (CA) 2021-06-08 US disclosed
CN-112469725-A Penicillin binding protein inhibitors 维纳拓尔斯制药公司 2021-03-09 CN disclosed
CN-112295741-A Test method for recovering and concentrating sulfide ore 江西浒坑钨业有限公司 2021-02-02 CN disclosed
EP-3630783-A1 PENICILLIN-BINDING PROTEIN INHIBITORS Venatorx Pharmaceuticals, Inc. (US) 2020-04-08 EP disclosed
US-20200102331-A1 PENICILLIN-BINDING PROTEIN INHIBITORS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2020-04-02 US disclosed
US-4327093-A TREATING INFECTIONS DISEASES, ANTIBACTERIAL ACTIVITY FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1982-04-27 US disclosed
EP-0030630-A2 7-Acylamino-3-vinylcephalosporanic acid derivatives, processes for their preparation, pharmaceutical compositions containing them; their starting compounds and their preparation FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-06-24 EP disclosed
US-4268509-A BACTERICIDES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-05-19 US disclosed
EP-0027599-A2 Cephem compounds, processes for their preparation and pharmaceutical compositions containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1981-04-29 EP disclosed
US-4234724-A OXADETHIACEPHEMCARBOXYLIC ACIDS FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) 1980-11-18 US disclosed
EP-0010313-A1 3,7-Disubstituted-2- or -3-cephem-4-carboxylic acid compounds, pharmaceutical compositions containing them and processes for the preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-04-30 EP disclosed
EP-0007470-A2 Cephem compounds, processes for their preparation and pharmaceutical compositions containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1980-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11267826-B2 Penicillin-binding protein inhibitors PEPD, BPGM, EBPL LMNA 3468/4885GAA 345/4885MAPT 3146/4885
US-20200102331-A1 PENICILLIN-BINDING PROTEIN INHIBITORS PEPD, BPGM, EBPL LMNA 3468/4885GAA 345/4885MAPT 3146/4885
US-11028103-B2 Derivatized 3-styryl-cephalosporins PEPD, SI, NAALAD2 LMNA 532/4885GAA 56/4885MAPT 4037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.