Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2446043 | 0.86 | HCRTR1 (0.32) | — | |
| SCHEMBL2452086 | 0.81 | — | — | |
| SCHEMBL2387383 | 0.75 | GPR119 (0.33) | — | |
| SCHEMBL2446217 | 0.73 | HTR2B (0.34) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL1914291 | 0.70 | — | — | |
| SCHEMBL2450982 | 0.69 | CYP2C9 (0.30) | — | |
| SCHEMBL14849166 | 0.69 | GABRG2 (0.38) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL16767137 | 0.69 | CDC7 (0.34) | — | |
| SCHEMBL2482178 | 0.69 | — | — | |
| SCHEMBL2413611 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119853-A1 | ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-09-29 | — | — | WO | disclosed |