Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.32 |
| ▸ | IDO1 | P14902 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KIT | P10721 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2454367 | 0.86 | GABRA1 (0.31) | — | |
| SCHEMBL2386864 | 0.84 | PRKCZ (0.31) | — | |
| SCHEMBL2387383 | 0.78 | GPR119 (0.33) | — | |
| SCHEMBL2413611 | 0.78 | — | — | |
| SCHEMBL1293968 | 0.77 | HCRTR1 (0.41) | HCRTR1HCRTR2 | |
| SCHEMBL16767137 | 0.76 | CDC7 (0.34) | — | |
| SCHEMBL2411410 | 0.74 | HRH4 (0.40) | IDO1MEN1POLBKMT2A | |
| SCHEMBL1914291 | 0.74 | — | — | |
| SCHEMBL1914244 | 0.74 | — | — | |
| SCHEMBL2373487 | 0.72 | DAGLA (0.34) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119853-A1 | ANALOGUES FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2011-09-29 | — | — | WO | disclosed |