Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.49 |
| ▸ | NPC1 | O15118 | 8/20 | 0.49 |
| ▸ | RAB9A | P51151 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2765541 | 0.93 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL2458919 | 0.85 | RAB9A (0.49) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL2454381 | 0.83 | DYRK1A (0.39) | SMN1; SMN2NPC1RAB9AKDM4EMAPT | |
| SCHEMBL2766524 | 0.79 | RAB9A (0.44) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| Butadiene SCHEMBL2766054 | 0.76 | RAB9A (0.42) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL14996633 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL2460517 | 0.74 | CYP2A6 (0.53) | ALDH1A1KDM4EMAPTCYP2C19CYP1A2 | |
| SCHEMBL23400414 | 0.73 | NPC1 (0.42) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL14996561 | 0.73 | NPC1 (0.50) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL10103967 | 0.73 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2371831-B1 | PROCESS FOR PRODUCING ORGANOLITHIUM COMPOUND AND PROCESS FOR PRODUCING SUBSTITUTED AROMATIC COMPOUND | NIPPON SODA CO (JP) | 2016-09-07 | — | — | EP | disclosed |
| US-9133098-B2 | Process for producing organolithium compound and process for producing substituted aromatic compound | NIPPON SODA CO., LTD. (JP) | 2015-09-15 | — | — | US | disclosed |
| US-20150025276-A1 | PROCESS FOR PRODUCING ORGANOLITHIUM COMPOUND AND PROCESS FOR PRODUCING SUBSTITUTED AROMATIC COMPOUND | NIPPON SODA CO., LTD. (JP) | 2015-01-22 | — | — | US | disclosed |
| US-8871970-B2 | Process for producing organolithium compound and process for producing substituted aromatic compound | NIPPON SODA CO., LTD. (JP) | 2014-10-28 | — | — | US | disclosed |
| EP-2371831-A1 | PROCESS FOR PRODUCING ORGANOLITHIUM COMPOUND AND PROCESS FOR PRODUCING SUBSTITUTED AROMATIC COMPOUND | Nippon Soda Co., Ltd. (JP) | 2011-10-05 | — | — | EP | disclosed |
| US-20110224457-A1 | PROCESS FOR PRODUCING ORGANOLITHIUM COMPOUND AND PROCESS FOR PRODUCING SUBSTITUTED AROMATIC COMPOUND | NIPPON SODA CO., LTD. | 2011-09-15 | — | — | US | disclosed |
| US-7368516-B2 | Catalyst for trimerization of ethylene and process for trimerizing ethylene using the catalyst | TOSOH CORPORATION (JP) | 2008-05-06 | — | — | US | disclosed |
| US-20050187419-A1 | Catalyst for trimerization of ethylene and process for trimerizing ethylene using the catalyst | TOSOH CORPORATION (JP) | 2005-08-25 | — | — | US | disclosed |
| US-6900152-B2 | Catalyst for trimerization of ethylene and process for trimerizing ethylene using the catalyst | TOSOH CORPORATION (JP) | 2005-05-31 | — | — | US | disclosed |
| US-20020035029-A1 | Catalyst for trimerization of ethylene and process for trimerizing ethylene using the catalyst | TOSOH CORPORATION (JP) | 2002-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187419-A1 | Catalyst for trimerization of ethylene and process for trimerizing ethylene using the catalyst | ACMSD, TAF9, ETV6 | SMN1; SMN2 3774/4885NPC1 3818/4885RAB9A 4100/4885 |
| US-20110224457-A1 | PROCESS FOR PRODUCING ORGANOLITHIUM COMPOUND AND PROCESS FOR PRODUCING SUBSTITUTED AROMATIC COMPOUND | C9, TRPA1, PKD1 | SMN1; SMN2 4349/4885NPC1 382/4885RAB9A 2993/4885 |
| US-20150025276-A1 | PROCESS FOR PRODUCING ORGANOLITHIUM COMPOUND AND PROCESS FOR PRODUCING SUBSTITUTED AROMATIC COMPOUND | C9, TRPA1, PKD1 | SMN1; SMN2 4349/4885NPC1 382/4885RAB9A 2993/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.