Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 8/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 7/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2452397 | 0.90 | GPR119 (0.64) | GPR119 | |
| SCHEMBL2456911 | 0.87 | GPR119 (0.44) | GPR119 | |
| SCHEMBL2458824 | 0.85 | GPR119 (0.54) | GPR119 | |
| SCHEMBL2452868 | 0.85 | GPR119 (0.63) | GPR119 | |
| SCHEMBL2452652 | 0.84 | GPR119 (0.41) | GPR119 | |
| SCHEMBL2454874 | 0.83 | GPR119 (0.66) | GPR119 | |
| SCHEMBL2452808 | 0.83 | GPR119 (0.42) | GPR119 | |
| SCHEMBL2458838 | 0.82 | GPR119 (0.46) | GPR119 | |
| SCHEMBL2452245 | 0.82 | GPR119 (0.48) | GPR119 | |
| SCHEMBL2453891 | 0.80 | GPR119 (0.47) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170864-B1 | PYRIDONE GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2011-09-14 | — | — | EP | claimed |