Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2452245 | 0.90 | GPR119 (0.48) | GPR119KCNH2MCHR1 | |
| SCHEMBL2452652 | 0.87 | GPR119 (0.41) | GPR119MCHR1GPR6 | |
| SCHEMBL2454637 | 0.87 | GPR119 (0.52) | GPR119 | |
| SCHEMBL2452808 | 0.86 | GPR119 (0.42) | GPR119EPHX2MCHR1 | |
| SCHEMBL2458838 | 0.85 | GPR119 (0.46) | GPR119MCHR1 | |
| SCHEMBL2453891 | 0.83 | GPR119 (0.47) | GPR119EPHX2KCNH2MCHR1 | |
| SCHEMBL2450627 | 0.82 | GPR119 (0.51) | GPR119MCHR1 | |
| SCHEMBL2452397 | 0.82 | GPR119 (0.64) | GPR119MCHR1 | |
| SCHEMBL2450082 | 0.82 | GPR119 (0.56) | GPR119EPHX2MCHR1FFAR1 | |
| SCHEMBL2452869 | 0.81 | GPR119 (0.45) | GPR119MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170864-B1 | PYRIDONE GPR119 G PROTEIN-COUPLED RECEPTOR AGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2011-09-14 | — | — | EP | claimed |