Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.36 |
| ▸ | NPC1 | O15118 | 7/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24547734 | 0.89 | SMN1; SMN2 (0.45) | RAB9ANPC1HPGDALDH1A1KDM4E | |
| SCHEMBL27267989 | 0.89 | CNR1 (0.42) | RAB9ANPC1HPGDALDH1A1CNR2 | |
| SCHEMBL24547768 | 0.87 | NCF1 (0.36) | RAB9ANPC1CNR2SMN1; SMN2KMT2A | |
| SCHEMBL29650940 | 0.80 | KDM4E (0.35) | HPGDALDH1A1KDM4EALOX15HSD17B10 | |
| SCHEMBL24468603 | 0.80 | KDM4E (0.35) | HPGDALDH1A1KDM4EALOX15HSD17B10 | |
| SCHEMBL29686097 | 0.78 | KDM4E (0.32) | KDM4E | |
| SCHEMBL24468209 | 0.78 | KDM4E (0.32) | KDM4E | |
| Hydrochloric Acid SCHEMBL29106338 | 0.77 | KDM4E (0.31) | KDM4E | |
| Hydrochloric Acid SCHEMBL29686221 | 0.77 | KDM4E (0.31) | KDM4E | |
| SCHEMBL24541157 | 0.76 | CCNC (0.35) | SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022132914-A1 | PRMTS INHIBITORS | AMGEN INC. (US) | 2022-06-23 | — | — | WO | disclosed |