SCHEMBL24547765

SCHEMBL24547765

Cn1ncc2c1c1ccccc1n2C(=O)Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
LMNA P02545 5/20 0.44
HPGD P15428 4/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44
HTR7 P34969 9/20 0.41
HSD17B10 Q99714 3/20 0.40
ALDH1A1 P00352 3/20 0.40
GLA P06280 1/20 0.40
GAA P10253 1/20 0.40
CYP1A2 P05177 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C19 P33261 1/20 0.38
CNR2 P34972 1/20 0.38
NR3C1 P04150 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24547759 0.81 HTR7 (0.53) HTR7
SCHEMBL12732178 0.80 HTR7 (0.52) KDM4EL3MBTL1LMNAHTTHTR7
SCHEMBL24547742 0.80 P2RX4 (0.56) KDM4ELMNAHPGDMAPK1HTT
SCHEMBL24547744 0.79 KDM4E (0.45) KDM4EL3MBTL1LMNAHPGDMAPK1
SCHEMBL24547635 0.77 KDM4E (0.47) KDM4ELMNAHPGDHTTHSD17B10
SCHEMBL27113220 0.77 HTR7 (0.48) HTR7
SCHEMBL24547754 0.74 HPGD (0.42) KDM4EL3MBTL1LMNAHPGDMAPK1
SCHEMBL24547758 0.74 ELANE (0.46) KDM4ELMNAHPGDMAPK1HTT
SCHEMBL24547658 0.74 LMNA (0.67) KDM4ELMNAHPGDHTTALDH1A1
SCHEMBL24547630 0.74 LMNA (0.48) KDM4ELMNAHPGDMAPK1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067654-A1 OXYTOCIN RECEPTOR MODULATORS Kinoxis Therapeutics Pty Ltd (AU) 2024-02-29 US disclosed
US-20240067654-A1 OXYTOCIN RECEPTOR MODULATORS Kinoxis Therapeutics Pty Ltd (AU) 2024-02-29 US disclosed
WO-2022126179-A1 OXYTOCIN RECEPTOR MODULATORS THE UNIVERSITY OF SYDNEY (AU) 2022-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240067654-A1 OXYTOCIN RECEPTOR MODULATORS OXTR, AVPR1B, AVPR1A KDM4E 4374/4885L3MBTL1 4471/4885LMNA 2876/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.