SCHEMBL24548685

[N-]=[N+]=NCOC1CC(n2cc(C#CCNC(=O)COC(COc3cccc(C(=O)NCCCCCNC(=O)CCCCCNC(=O)COc4cc(S(=O)(=O)O)c5ccc6c(S(=O)(=O)O)cc(S(=O)(=O)O)c7ccc4c5c76)c3)N=[N+]=[N-])c(N)nc2=O)OC1COP(=O)(O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.35

Predicted protein targets (top 3)

	gene	UniProt	supporting neighbours	confidence
▸	P2RY2	P41231	3/20	0.35

▸	P2RY6	Q15077	2/20	0.35

▸	P2RY4	P51582	1/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24548686	0.92	POLB (0.34)	P2RY2P2RY6P2RY4
SCHEMBL24570761	0.90	P2RY2 (0.33)	P2RY2P2RY6P2RY4
SCHEMBL23419185	0.89	P2RY2 (0.32)	P2RY2P2RY6P2RY4
SCHEMBL26082650	0.84	POLB (0.34)	P2RY2P2RY6P2RY4
SCHEMBL14806824	0.83	P2RY2 (0.32)	P2RY2P2RY6P2RY4
SCHEMBL20383456	0.83	P2RY2 (0.32)	P2RY2P2RY6P2RY4
SCHEMBL20387883	0.83	P2RY2 (0.32)	P2RY2P2RY6P2RY4
SCHEMBL20021614	0.83	P2RY2 (0.32)	P2RY2P2RY6P2RY4
SCHEMBL14820564	0.83	P2RY2 (0.32)	P2RY2P2RY6P2RY4
SCHEMBL14392447	0.83	P2RY2 (0.32)	P2RY2P2RY6P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20220195518-A1	METHODS AND COMPOSITIONS FOR NUCLEIC ACID SEQUENCING	ILLUMINA CAMBRIDGE LIMITED (GB)	2022-06-23	—	—	US	disclosed