Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 12/20 | 0.85 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.81 |
| ▸ | CNR2 | P34972 | 1/20 | 0.81 |
| ▸ | MAPT | P10636 | 3/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.80 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.80 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.79 |
| ▸ | PTGES | O14684 | 1/20 | 0.79 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.79 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.79 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.79 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | ALB | P02768 | 1/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.79 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.79 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxametacin SCHEMBL29378857 | 1.00 | PTGS1 (1.00) | PTGS1PTGS2AKR1C3CNR2MAPT | |
| SCHEMBL14405006 | 0.92 | PTGS2 (1.00) | PTGS1PTGS2AKR1C3CNR2MAPT | |
| SCHEMBL20259394 | 0.91 | PTGS2 (0.83) | PTGS1PTGS2AKR1C3CNR2MAPT | |
| SCHEMBL9657228 | 0.91 | PTGS1 (0.85) | PTGS1PTGS2AKR1C3CNR2MAPT | |
| SCHEMBL14398315 | 0.90 | PTGS1 (0.82) | PTGS1PTGS2AKR1C3CNR2MAPT | |
| SCHEMBL5107049 | 0.90 | PTGS2 (0.82) | PTGS1PTGS2AKR1C3CNR2MAPT | |
| SCHEMBL5112013 | 0.90 | PTGS2 (0.84) | PTGS1PTGS2 | |
| SCHEMBL30426824 | 0.89 | PTGS2 (1.00) | PTGS1PTGS2AKR1C3CNR2MAPT | |
| SCHEMBL14086813 | 0.89 | PTGS2 (1.00) | PTGS1PTGS2AKR1C3CNR2MAPT | |
| SCHEMBL17378074 | 0.89 | PTGS2 (0.80) | PTGS1PTGS2AKR1C3CNR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1944 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240041935-A1 | PREVENTION AND TREATMENT OF REPRODUCTIVE FAILURE BY REGENERATIVE CELLS AND ADJUVANTS | CREATIVE MEDICAL TECHNOLOGIES, INC. (US) | 2024-02-08 | — | — | US | claimed |
| EP-2709663-B1 | USE OF ANTI-CGRP ANTIBODIES AND ANTIBODY FRAGMENTS TO PREVENT OR INHIBIT PHOTOPHOBIA OR LIGHT AVERSION IN SUBJECTS IN NEED THEREOF, ESPECIALLY MIGRAINE SUFFERERS | ALDERBIO HOLDINGS LLC (US) | 2019-03-20 | — | — | EP | claimed |
| US-20170128383-A1 | Polymeric Adhesive Matrix with Salified Carboxylic Groups for Transdermal Use | BOUTY S.P.A. (IT) | 2017-05-11 | — | — | US | claimed |
| CN-102292106-B | IL-6 antibody and uses thereof | ALDER BIOPHARMACEUTICALS, INC. (US) | 2016-02-03 | — | — | CN | claimed |
| US-8865198-B2 | Method for treating a periodontal disease | DEXCEL PHARMA TECHNOLOGIES LTD. (IL) | 2014-10-21 | — | — | US | claimed |
| US-20140080911-A1 | Polymeric Adhesive Matrix with Salified Carboxylic Groups for Transdermal Use | BOUTY S P A (IT) | 2014-03-20 | — | — | US | claimed |
| EP-2560634-A1 | NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS | Piramal Enterprises Limited (IN) | 2013-02-27 | — | — | EP | claimed |
| US-8361492-B2 | Drug delivery system and methods of use | Ocugenics, LLC (US) | 2013-01-29 | — | — | US | claimed |
| EP-2455064-A1 | Device for treating a periodontal disease | Dexcel Pharma Technologies Ltd. (IL) | 2012-05-23 | — | — | EP | claimed |
| EP-2448558-A1 | LOCAL THERAPEUTIC RELEASE DEVICE | Dexcel Pharma Technologies Ltd. (IL) | 2012-05-09 | — | — | EP | claimed |
| EP-1073470-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2001-02-07 | — | — | EP | claimed |
| WO-2000048636-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS | INPHARMA S.A. (CH) | 2000-08-24 | — | — | WO | claimed |
| EP-0786999-A4 | COMBINATION METHOD FOR ACNE TREATMENT | MERCK & CO INC (US) | 1999-01-20 | — | — | EP | claimed |
| EP-0792371-A4 | COMBINATION METHOD FOR ACNE TREATMENT | MERCK & CO INC (US) | 1998-12-30 | — | — | EP | claimed |
| EP-0792371-A1 | COMBINATION METHOD FOR ACNE TREATMENT | Merck & Co., Inc. (US) | 1997-09-03 | — | — | EP | claimed |
| EP-0786999-A1 | COMBINATION METHOD FOR ACNE TREATMENT | Merck & Co., Inc. (US) | 1997-08-06 | — | — | EP | claimed |
| US-5543417-A | 5 Alpha-reductase inhibitor and at least one of an antibacterial agent, a keratolytic agent or an anti-inflammatory agent | MERCK & CO., INC. (US) | 1996-08-06 | — | — | US | claimed |
| WO-1996012817-A1 | COMBINATION METHOD FOR ACNE TREATMENT | MERCK & CO., INC. (US) | 1996-05-02 | — | — | WO | claimed |
| WO-1996012487-A1 | COMBINATION METHOD FOR ACNE TREATMENT | MERCK & CO., INC. (US) | 1996-05-02 | — | — | WO | claimed |
| US-4455432-A | Process for the preparation of 1-(4-chloro-benzoyl)-5-methoxy-2-methyl-3-indolyl-acetohydroxamic acid | UNIBIOS S.P.A. (IT) | 1984-06-19 | — | — | US | claimed |