Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | PLK4 | O00444 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25805641 | 0.79 | NOS1 (0.39) | HTTPTK2NOS1 | |
| SCHEMBL29684443 | 0.79 | NOS1 (0.39) | HTTPTK2NOS1 | |
| SCHEMBL20674123 | 0.79 | HTT (0.47) | HTTPTK2NOS1MAPTSLC2A1 | |
| SCHEMBL21958684 | 0.76 | HTT (0.44) | HTTPTK2MAPTSLC2A1 | |
| SCHEMBL4830696 | 0.76 | NOS1 (0.37) | HTTPTK2NOS1MAPT | |
| SCHEMBL29863669 | 0.76 | NOS1 (0.37) | HTTPTK2NOS1SLC2A1 | |
| SCHEMBL4838398 | 0.76 | NOS1 (0.37) | HTTPTK2NOS1 | |
| SCHEMBL22119097 | 0.76 | HTT (0.36) | HTTPTK2NOS1 | |
| SCHEMBL30774307 | 0.76 | HTT (0.36) | HTTPTK2NOS1KMT2A | |
| SCHEMBL25805690 | 0.76 | HTT (0.36) | HTTPTK2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133037-A1 | MACROCYCLES AND THEIR USE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2022-06-23 | — | — | WO | disclosed |