Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24553744 | 0.79 | HTT (0.44) | NOS1HTTPTK2 | |
| SCHEMBL4830696 | 0.79 | NOS1 (0.37) | NOS1HTTPTK2 | |
| SCHEMBL29863669 | 0.79 | NOS1 (0.37) | NOS1HTTPTK2 | |
| SCHEMBL4838398 | 0.79 | NOS1 (0.37) | NOS1HTTPTK2 | |
| SCHEMBL4106173 | 0.79 | DPP4 (0.43) | NOS1HTTPTK2 | |
| SCHEMBL29864632 | 0.75 | NOS1 (0.34) | NOS1HTTPTK2 | |
| SCHEMBL30774307 | 0.75 | HTT (0.36) | NOS1HTTPTK2 | |
| SCHEMBL22119097 | 0.75 | HTT (0.36) | NOS1HTTPTK2 | |
| SCHEMBL30097193 | 0.72 | HTT (0.49) | NOS1HTTDYRK1A | |
| SCHEMBL25267720 | 0.71 | CLK1 (0.38) | NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119431323-A | Heterobicyclic amides as CD38 inhibitors | 贝林格尔·英格海姆国际有限公司 | 2025-02-14 | — | — | CN | disclosed |
| CN-114423753-B | Heterobicyclic amides as CD38 inhibitors | 里邦医疗公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-114656487-B | Fused pyrimidine compound, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2023-11-14 | — | — | CN | disclosed |
| CN-114656487-A | Condensed pyrimidine compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2022-06-24 | — | — | CN | disclosed |