SCHEMBL2455413

SCHEMBL2455413

COc1ccc(C=C(C)C(=O)c2ccc(N)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.53
CES1 P23141 2/20 0.53
MAPT P10636 3/20 0.51
ALDH1A1 P00352 3/20 0.51
KDM4E B2RXH2 1/20 0.51
HPGD P15428 1/20 0.51
TDP1 Q9NUW8 2/20 0.48
MAPK1 P28482 1/20 0.48
CYP3A4 P08684 2/20 0.47
F3 P13726 1/20 0.46
TUBB1 Q9H4B7 2/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
PARP1 P09874 1/20 0.46
PARP10 Q53GL7 1/20 0.46
PARP2 Q9UGN5 1/20 0.46
PARP4 Q9UKK3 1/20 0.46
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
TUBB4A P04350 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2455411 1.00 CES2 (0.53) CES2CES1MAPTALDH1A1KDM4E
SCHEMBL15304532 0.92 CES2 (0.62) CES2CES1MAPTALDH1A1KDM4E
SCHEMBL27301045 0.84 CES2 (0.64) CES2CES1MAPTALDH1A1KDM4E
SCHEMBL6936154 0.84 NPC1 (0.53) MAPTALDH1A1TDP1PARP10MAOA
SCHEMBL6936156 0.84 NPC1 (0.53) MAPTALDH1A1TDP1PARP10MAOA
SCHEMBL5697760 0.83 NQO2 (0.56) MAPTALDH1A1KDM4EHPGDCYP3A4
SCHEMBL5697759 0.83 NQO2 (0.56) MAPTALDH1A1KDM4EHPGDCYP3A4
SCHEMBL2546691 0.82 ABCG2 (0.48) MAPTALDH1A1KDM4ECYP3A4
SCHEMBL2457460 0.82 TSHR (0.50) MAPTALDH1A1CYP3A4
SCHEMBL2457458 0.82 TSHR (0.50) MAPTALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12292665-B2 Bistable liquid crystal dispersion devices comprising metal-organic mesogens and applications thereof GAUZY LTD. (IL) 2025-05-06 US disclosed
US-20220050316-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF GAUZY LTD. (IL) 2022-02-17 US disclosed
US-10851302-B2 Metal organic liquid crystal dyes GAUZY LTD. (IL) 2020-12-01 US disclosed
US-10705262-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2020-07-07 US disclosed
EP-3209748-B1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD (IL) 2020-05-06 EP disclosed
EP-2553520-B1 POLYMER-STABILIZED THERMOTROPIC LIQUID CRYSTAL DEVICE RAVENBRICK LLC (US) 2019-07-31 EP disclosed
US-20190212477-A1 Liquid Crystal Half-Wave Plate Lens META PLATFORMS TECHNOLOGIES, LLC 2019-07-11 US disclosed
US-10247858-B2 Liquid crystal half-wave plate lens FACEBOOK TECHNOLOGIES, LLC (US) 2019-04-02 US disclosed
US-20170355908-A1 METAL ORGANIC LIQUID CRYSTAL DYES GAUZY LTD. (IL) 2017-12-14 US disclosed
US-20170336663-A1 BISTABLE LIQUID CRYSTAL DISPERSION DEVICES COMPRISING METAL-ORGANIC MESOGENS AND APPLICATIONS THEREOF GAUZY LTD. (IL) 2017-11-23 US disclosed
EP-0747461-B1 Polymer stabilized liquid crystals and flexible devices thereof SNIARICERCHE S C P A (IT) 2001-09-05 EP disclosed
US-6049366-A PLACING A LIQUID CRYSTAL FLUID COMPRISING LIQUID CRYSTAL, A PREPOLYMER, AND MICROPARTICLES BETWEEN FLEXIBLE CONDUCTIVE SUBSTRATES; LAMINATING THE SUBSTRATE TOGETHER, CURING THE FLUID LIQUID CRYSTAL COMPRISING THE PREPOLYMER SNIARICERCHE S.C.P.A. (IT) 2000-04-11 US disclosed
EP-0656927-B1 METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX SNIARICERCHE S C P A (IT) 1999-12-01 EP disclosed
EP-0927753-A1 Liquid crystal dispersed polymer electrooptical films having reverse morphology Sniaricerche S.C.P.A. (IT) 1999-07-07 EP disclosed
US-5843333-A Metallo organo liquid crystals in a polymer matrix SNIARICERCHE S.C.P.A (IT) 1998-12-01 US disclosed
EP-0787782-A2 Process and materials for highly transparent polymer dispersed liquid crystals Sniaricerche S.C.P.A. (IT) 1997-08-06 EP disclosed
EP-0747461-A1 Polymer stabilized liquid crystals and flexible devices thereof Sniaricerche S.C.P.A. (IT) 1996-12-11 EP disclosed
WO-1995001410-A1 METALLO ORGANO LIQUID CRYSTALS IN A POLYMER MATRIX SNIARICERCHE S.C.P.A. (IT) 1995-01-12 WO disclosed
US-4101207-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1978-07-18 US disclosed
US-3935337-A Preparation of liquid crystal containing polymeric structure OWENS-ILLINOIS, INC. (US) 1976-01-27 US disclosed