Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | STAT3 | P40763 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | FLT3 | P36888 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29805260 | 0.76 | KDM4E (1.00) | KDM4ESTAT3HIF1AFLT3ALDH1A1 | |
| SCHEMBL498053 | 0.76 | KDM4E (1.00) | KDM4ESTAT3HIF1AFLT3ALDH1A1 | |
| SCHEMBL9722754 | 0.75 | ALDH1A1 (0.61) | KDM4EALDH1A1GAAMEN1MAPT | |
| SCHEMBL21449273 | 0.73 | KDM4E (0.68) | KDM4ESTAT3HIF1AFLT3ALDH1A1 | |
| SCHEMBL9806950 | 0.71 | CISD2 (0.57) | KDM4EALDH1A1GAAMEN1MAPT | |
| SCHEMBL31148407 | 0.71 | KDM4E (0.66) | KDM4ESTAT3HIF1AFLT3ALDH1A1 | |
| SCHEMBL7668372 | 0.71 | KDM4E (0.66) | KDM4ESTAT3HIF1AFLT3ALDH1A1 | |
| SCHEMBL22462466 | 0.70 | MEN1 (0.66) | KDM4ESTAT3HIF1AFLT3ALDH1A1 | |
| SCHEMBL24554622 | 0.69 | KDM4E (0.53) | KDM4ESTAT3HIF1AFLT3ALDH1A1 | |
| SCHEMBL9722802 | 0.69 | CISD2 (0.60) | KDM4EALDH1A1GAAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133480-A1 | ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-06-23 | — | — | WO | disclosed |