Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.66 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.66 |
| ▸ | STAT3 | P40763 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.66 |
| ▸ | FLT3 | P36888 | 2/20 | 0.62 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.62 |
| ▸ | CDK2 | P24941 | 1/20 | 0.62 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.62 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.60 |
| ▸ | WNT3A | P56704 | 3/20 | 0.60 |
| ▸ | IDO1 | P14902 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | EPHB3 | P54753 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | FLT1 | P17948 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31148407 | 1.00 | KDM4E (0.66) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| SCHEMBL5792748 | 0.89 | CTNNB1 (0.67) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| SCHEMBL5353834 | 0.86 | FLT3 (0.65) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| SCHEMBL29444537 | 0.86 | FLT3 (0.65) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| SCHEMBL42245 | 0.86 | FLT3 (0.65) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| SCHEMBL4469913 | 0.84 | KDR (0.55) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| SCHEMBL4469917 | 0.84 | IDO1 (0.56) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| SCHEMBL967165 | 0.84 | KDM4E (0.62) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| SCHEMBL591861 | 0.84 | KDM4E (0.62) | KDM4EYTHDC1STAT3HIF1AFLT3 | |
| SCHEMBL82761 | 0.84 | KDM4E (0.62) | KDM4EYTHDC1STAT3HIF1AFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117386893-A | Multilayer composite antibacterial PE water supply pipeline and preparation process thereof | 江苏惠升管业集团有限公司 | 2024-01-12 | — | — | CN | claimed |
| US-20130245033-A1 | AMIDE COMPOUNDS | GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2013-09-19 | — | — | US | claimed |
| US-9238643-B2 | Amide compounds | GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2016-01-19 | — | — | US | disclosed |
| CN-102558074-B | Piperazine amide compound containing pyridazine substituent group | GUANGZHOU INST BIOMED & HEALTH | 2014-09-24 | — | — | CN | disclosed |
| CN-102382102-B | Amide compound | GUANGZHOU INST BIOMED & HEALTH | 2014-01-08 | — | — | CN | disclosed |
| US-20130245033-A1 | AMIDE COMPOUNDS | GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2013-09-19 | — | — | US | disclosed |
| CN-101851211-B | Piperazine amide compound | JIANGSU CHIA TAI TIANQING PHAR | 2013-08-14 | — | — | CN | disclosed |
| CN-102558074-A | Piperazine amide compound containing pyridazine substituent group | GUANGZHOU INST BIOMED & HEALTH | 2012-07-11 | — | — | CN | disclosed |
| CN-102382102-A | Amide compound | GUANGZHOU INST BIOMED & HEALTH | 2012-03-21 | — | — | CN | disclosed |
| CN-101851211-A | Novel piperazine amide compound | JIANGSU CHIA TAI TIANQING PHAR | 2010-10-06 | — | — | CN | disclosed |
| US-6372778-B1 | AMINE HYDROXYALKYL SULFONAMIDE AS ENZYME INHIBITORS | VERTEX PHARMACEUTICALS, INCORPORATED | 2002-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130245033-A1 | AMIDE COMPOUNDS | AR, AVPR2, H1-0 | KDM4E 2212/4885YTHDC1 2181/4885STAT3 374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.