SCHEMBL2456063

SCHEMBL2456063

O=C(O)C(=O)C(=S)Cc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.54
CES2 O00748 1/20 0.54
AKR1B1 P15121 1/20 0.54
CTBP2 P56545 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
FNTA P49354 1/20 0.45
FNTB P49356 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
ALDH1A1 P00352 1/20 0.44
MAPK1 P28482 1/20 0.44
EPHX2 P34913 1/20 0.44
GAA P10253 2/20 0.43
PAM P19021 2/20 0.42
TSHR P16473 2/20 0.42
ABCC4 O15439 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6723396 0.86 CES1 (0.58) CES1CES2AKR1B1CTBP2MEN1
Phenylpyruvate SCHEMBL9557730 0.79 CES1 (0.61) CES1CES2AKR1B1CTBP2MEN1
SCHEMBL711308 0.79 CES1 (0.50) CES1CES2AKR1B1CTBP2MEN1
SCHEMBL3268826 0.78 CES1 (0.54) CES1CES2AKR1B1CTBP2MEN1
SCHEMBL27619700 0.77 CES1 (0.73) CES1CES2AKR1B1CTBP2MEN1
SCHEMBL7537694 0.74 CES1 (0.67) CES1CES2AKR1B1CTBP2MEN1
SCHEMBL6615876 0.74 CES1 (0.54) CES1CES2AKR1B1CTBP2MEN1
SCHEMBL8616006 0.74 CES2 (0.48) CES1CES2AKR1B1MEN1KMT2A
SCHEMBL7269859 0.73 CES1 (0.73) CES1CES2AKR1B1CTBP2MEN1
Phenylpyruvate SCHEMBL9557735 0.72 CES1 (0.64) CES1CES2AKR1B1CTBP2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2550251-A1 PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACID OR SALT THEREOF Sumitomo Chemical Company, Limited (JP) 2013-01-30 EP disclosed
WO-2011118849-A1 PROCESS FOR PRODUCING SULFUR-CONTAINING AMINO ACID OR SALT THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-09-29 WO disclosed