Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | PAM | P19021 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6723396 | 0.83 | CES1 (0.58) | CES1CES2AKR1B1CTBP2MEN1 | |
| SCHEMBL2456063 | 0.79 | CES1 (0.54) | CES1CES2AKR1B1CTBP2MEN1 | |
| Phenylpyruvate SCHEMBL9557730 | 0.76 | CES1 (0.61) | CES1CES2AKR1B1CTBP2MEN1 | |
| SCHEMBL9618267 | 0.76 | ALDH1A1 (0.41) | CES1CES2AKR1B1MEN1KMT2A | |
| SCHEMBL3268826 | 0.75 | CES1 (0.54) | CES1CES2AKR1B1CTBP2MEN1 | |
| SCHEMBL2210068 | 0.74 | CYP2C19 (0.60) | KMT2ACYP3A4CYP2C9ALDH1A1GAA | |
| SCHEMBL41907 | 0.74 | CES1 (0.58) | CES1CES2AKR1B1CTBP2MEN1 | |
| SCHEMBL27564061 | 0.72 | CES1 (0.56) | CES1CES2AKR1B1CTBP2MEN1 | |
| Bromide SCHEMBL11497452 | 0.72 | CES1 (0.56) | CES1CES2AKR1B1CTBP2MEN1 | |
| Hydrochloric Acid SCHEMBL27862997 | 0.72 | CES1 (0.56) | CES1CES2AKR1B1CTBP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624048-B2 | Photochromic cyclic compound and curable composition containing the photochromic cyclic compound | TOKUYAMA CORPORATION (JP) | 2026-05-12 | — | — | US | disclosed |
| WO-2025070122-A1 | PHOTOCHROMIC COMPOSITION, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2025-04-03 | — | — | WO | disclosed |
| WO-2025057814-A1 | PHOTOCHROMIC COMPOSITION, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2025-03-20 | — | — | WO | disclosed |
| WO-2025041625-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2025-02-27 | — | — | WO | disclosed |
| WO-2025041624-A1 | PHOTOCHROMIC COMPOUND, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2025-02-27 | — | — | WO | disclosed |
| WO-2025028365-A1 | PHOTOCHROMIC COMPOUND, PHENOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASS | 株式会社トクヤマ | 2025-02-06 | — | — | WO | disclosed |
| WO-2024202086-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASS | 株式会社トクヤマ | 2024-10-03 | — | — | WO | disclosed |
| WO-2024202087-A1 | PHOTOCHROMIC COMPOUND, PROPARGYL ALCOHOL COMPOUND, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND SPECTACLES | 株式会社トクヤマ | 2024-10-03 | — | — | WO | disclosed |
| US-20230280500-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC CURABLE COMPOSITION, CURED BODY, LENS AND EYEGLASSES | TOKUYAMA CORPORATION (JP) | 2023-09-07 | — | — | US | disclosed |
| WO-2023140186-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2023-07-27 | — | — | WO | disclosed |
| US-20040094753-A1 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2004-05-20 | — | — | US | disclosed |
| EP-1394156-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-6365707-B1 | CATALYTIC POLYEPOXIDES OR POLYTHIOEPOXIDES AND AMINO COMPOUNDS | MITSUI CHEMICALS, INC. (JP) | 2002-04-02 | — | — | US | disclosed |
| EP-0778276-B1 | Photochromic chromene derivatives | TOKUYAMA CORP (JP) | 2001-05-09 | — | — | EP | disclosed |
| EP-1058133-A2 | Polymerizable composition and process for producing optical resin comprising the same | Mitsui Chemicals, Inc. (JP) | 2000-12-06 | — | — | EP | disclosed |
| EP-0696582-B1 | Polycyclic spirophthalimide derivatives, process for their preparation and their use as fulgimides | TOKUYAMA CORP (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-5808100-A | DURABILITY | TOKUYAMA CORPORATION (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0778276-A1 | Photochromic chromene derivatives | TOKUYAMA CORPORATION (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5631382-A | PHOTOCHROMIC LENSES | TOKUYAMA CORPORATION (JP) | 1997-05-20 | — | — | US | disclosed |
| EP-0696582-A1 | Polycyclic spirophthalimide derivatives, process for their preparation and their use as fulgimides | TOKUYAMA CORPORATION (JP) | 1996-02-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12624048-B2 | Photochromic cyclic compound and curable composition containing the photochromic cyclic compound | CCNL2, CRY2, CRY1 | CES1 4399/4885CES2 3088/4885AKR1B1 1255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.