Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.55 |
| ▸ | AR | P10275 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KDM1A | O60341 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24564684 | 0.93 | SIGMAR1 (0.54) | SIGMAR1HRH3ARMEN1ALDH1A1 | |
| SCHEMBL24564636 | 0.81 | SIGMAR1 (0.66) | SIGMAR1HRH3ARMEN1ALDH1A1 | |
| SCHEMBL24581230 | 0.79 | SIGMAR1 (0.54) | SIGMAR1HRH3ARMEN1ALDH1A1 | |
| SCHEMBL24564709 | 0.79 | SIGMAR1 (0.56) | SIGMAR1HRH3ARMEN1ALDH1A1 | |
| SCHEMBL24564650 | 0.79 | HRH3 (0.62) | SIGMAR1HRH3KDM1AMAOBMAOA | |
| SCHEMBL24564669 | 0.79 | SIGMAR1 (0.56) | SIGMAR1HRH3ARMEN1ALDH1A1 | |
| SCHEMBL24564901 | 0.79 | HRH3 (0.62) | SIGMAR1HRH3KDM1AMAOBMAOA | |
| SCHEMBL24564649 | 0.79 | HRH3 (0.62) | SIGMAR1HRH3KDM1AMAOBMAOA | |
| SCHEMBL24564716 | 0.79 | HRH3 (0.62) | SIGMAR1HRH3KDM1AMAOBMAOA | |
| SCHEMBL3656053 | 0.78 | SIGMAR1 (0.66) | SIGMAR1HRH3ARMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140464-A1 | COMPOUNDS AND METHODS FOR TREATING AUTOIMMUNE DISORDERS BY TARGETING HLA-DQ2 | IMMUNOMOLECULAR THERAPEUTICS, INC. (US) | 2022-06-30 | — | — | WO | disclosed |
| US-20220204471-A1 | Compounds and Methods for Treating Autoimmune Disorders by Targeting HLA-DQ2 | IMMUNOMOLECULAR THERAPEUTICS, INC. | 2022-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220204471-A1 | Compounds and Methods for Treating Autoimmune Disorders by Targeting HLA-DQ2 | HLA-DRB1, CD74, HLA-B | SIGMAR1 4552/4885HRH3 393/4885AR 4325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.