Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | PGD | P52209 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15720392 | 0.94 | LMNA (0.46) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL8524243 | 0.94 | TDP1 (0.50) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL5139535 | 0.80 | PDE4A (0.46) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL23151858 | 0.79 | USP2 (0.39) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL17797760 | 0.79 | USP2 (0.44) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL2123186 | 0.78 | PDE4A (0.45) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL2344719 | 0.78 | LMNA (0.42) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL18880920 | 0.78 | LMNA (0.42) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| Xylitol SCHEMBL4750185 | 0.78 | LMNA (0.59) | USP2SLCO1B1LMNAL3MBTL1TDP1 | |
| SCHEMBL8679740 | 0.77 | LMNA (0.40) | USP2SLCO1B1LMNAL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3625225-B1 | LDHA ACTIVITY INHIBITORS | ARCTIC PHARMA AS (NO) | 2022-06-29 | — | — | EP | disclosed |