SCHEMBL2344719

SCHEMBL2344719

CC(=O)OC[C@H](O)[C@@H](O)[C@H](O)CO

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TDP1 Q9NUW8 2/20 0.40
PDE4A P27815 1/20 0.40
USP2 O75604 4/20 0.38
CYP3A4 P08684 3/20 0.38
MAPT P10636 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
RECQL P46063 1/20 0.38
SLCO1B1 Q9Y6L6 1/20 0.38
ALDH1A1 P00352 3/20 0.37
HSD17B10 Q99714 1/20 0.37
KDM4E B2RXH2 2/20 0.35
HPGD P15428 1/20 0.33
MEN1 O00255 1/20 0.33
TP53 P04637 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33
PRKCA P17252 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18880920 1.00 LMNA (0.42) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL347295 0.96 LMNA (0.48) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL349280 0.96 LMNA (0.48) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL5909539 0.96 LMNA (0.48) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL8677624 0.94 TDP1 (0.50) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL8677620 0.94 TDP1 (0.50) LMNAL3MBTL1TDP1PDE4AUSP2
Formaldehyde SCHEMBL27533331 0.92 LMNA (0.44) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL13737428 0.86 TDP1 (0.42) LMNATDP1USP2CYP3A4MAPT
SCHEMBL5836245 0.85 ALDH1A1 (0.38) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL15790543 0.82 LMNA (0.42) LMNAL3MBTL1TDP1PDE4AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130196399-A1 SACCHAROMYCES STRAIN WITH ABILITY TO GROW ON PENTOSE SUGARS UNDER ANAEROBIC CULTIVATION CONDITIONS C5 LIGNO TECHNOLOGIES IN LUND AB (SE) 2013-08-01 US disclosed
US-8367393-B2 Saccharomyces strain with ability to grow on pentose sugars under anaerobic cultivation conditions C5 LIGNO TECHNOLOGIES LUND AB (SE) 2013-02-05 US disclosed
EP-2358863-A1 SACCHAROMYCES STRAIN WITH ABILITY TO GROW ON PENTOSE SUGARS UNDER ANAEROBIC CULTIVATION CONDITIONS C5 Ligno Technologies in Lund AB (SE) 2011-08-24 EP disclosed
WO-2010059095-A1 SACCHAROMYCES STRAIN WITH ABILITY TO GROW ON PENTOSE SUGARS UNDER ANAEROBIC CULTIVATION CONDITIONS BÄRBEL HAHN AB (SE) 2010-05-27 WO disclosed
EP-1942872-A2 CARBOXYALKYLCELLULOSE ESTERS FOR ADMINISTRATION OF POORLY SOLUBLE PHARMACEUTICALLY ACTIVE AGENTS EASTMAN CHEMICAL COMPANY (US) 2008-07-16 EP disclosed
US-7276546-B2 Carbohydrate esters and polyol esters as plasticizers for polymers, compositions and articles including such plasticizers and methods of using the same EASTMAN CHEMICAL COMPANY (US) 2007-10-02 US disclosed
US-20070178152-A1 Carboxyalkylcellulose esters for administration of poorly soluble pharmaceutically active agents EASTMAN CHEMICAL COMPANY 2007-08-02 US disclosed
WO-2007056205-A2 CARBOXYALKYLCELLULOSE ESTERS FOR ADMINISTRATION OF POORLY SOLUBLE PHARMACEUTICALLY ACTIVE AGENTS EASTMAN CHEMICAL COMPANY (US) 2007-05-18 WO disclosed
US-6977275-B2 Carbohydrate esters and polyol esters as plasticizers for polymers, compositions and articles including such plasticizers and methods of using the same EASTMAN CHEMICAL COMPANY (US) 2005-12-20 US disclosed
US-20050228084-A1 Novel carbohydrate esters and polyol esters as plasticizers for polymers, compositions and articles including such plasticizers and methods of using the same BUCHANAN CHARLES M 2005-10-13 US disclosed
EP-1465944-A1 NOVEL CARBOHYDRATE ESTERS AND POLYOL ESTERS AS PLASTICIZERS FOR POLYMERS, COMPOSITIONS AND ARTICLES INCLUDING SUCH PLASTICIZERS AND METHODS OF USING THE SAME EASTMAN CHEMICAL COMPANY (US) 2004-10-13 EP disclosed
US-20030171458-A1 Novel carbohydrate esters and polyol esters as plasticizers for polymers, compositions and articles including such plasticizers and methods of using the same EASTMAN CHEMICAL COMPANY 2003-09-11 US disclosed
WO-2003062314-A1 NOVEL CARBOHYDRATE ESTERS AND POLYOL ESTERS AS PLASTICIZERS FOR POLYMERS, COMPOSITIONS AND ARTICLES INCLUDING SUCH PLASTICIZERS AND METHODS OF USING THE SAME EASTMAN CHEMICAL COMPANY (US) 2003-07-31 WO disclosed
CN-1052928-C Self-hardening sand curing agent for casting and its preparation HUIYATONG CASTING MATERIAL CO (CN) 2000-05-31 CN disclosed
CN-1184010-A Self-hardening sand curing agent for casting and its preparation HUIYATONG CASTING MATERIAL CO (CN) 1998-06-10 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070178152-A1 Carboxyalkylcellulose esters for administration of poorly soluble pharmaceutically active agents CEL, LIPA, SI LMNA 3005/4885L3MBTL1 3929/4885TDP1 1183/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.